Martin Trepel

Phenotypic detection of clonotypic B cells in multiple myeloma by specific immunoglobulin ligands reveals their rarity in multiple myeloma.

Steps toward mapping the human vasculature by phage display.

In vivo phage display and vascular heterogeneity: implications for targeted medicine.

Severe cold hemagglutinin disease (CHD) successfully treated with rituximab.

Peptides targeting caspase inhibitors.

Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors.

Aminopeptidase A is a functional target in angiogenic blood vessels.

Hematologic and molecular spontaneous remission following sepsis in acute monoblastic leukemia with translocation (9;11): a case report and review of the literature.

Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection.

A hybrid vector for ligand-directed tumor targeting and molecular imaging.

The epitope recognized by rituximab.

Isolation of targeted AAV2 vectors from novel virus display libraries.

Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU.

Design and construction of targeted AAVP vectors for mammalian cell transduction.

Identification of their epitope reveals the structural basis for the mechanism of action of the immunosuppressive antibodies basiliximab and daclizumab.

Vectors selected from adeno-associated viral display peptide libraries for leukemia cell-targeted cytotoxic gene therapy.

Meeting report: innovations in prostate cancer research.

Drug delivery in acute myeloid leukemia.

Chapter 4. Screening phage-display Peptide libraries for vascular targeted peptides.

Successful expansion but not complete restriction of tropism of adeno-associated virus by in vivo biopanning of random virus display peptide libraries.

A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer.

Adeno-associated viral vectors and their redirection to cell-type specific receptors.

Lapatinib.

Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells.

B-cell receptor epitope recognition correlates with the clinical course of chronic lymphocytic leukemia.

Peptide ligands incorporated into the threefold spike capsid domain to re-direct gene transduction of AAV8 and AAV9 in vivo.

Anti-tumor activity of a B-cell receptor-targeted peptide in a novel disseminated lymphoma xenograft model.

Immune response as a possible mechanism of long-lasting disease control in spontaneous remission of MLL/AF9-positive acute myeloid leukemia.

Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients.

Novel cytotoxic vectors based on adeno-associated virus.

Development and validation of novel AAV2 random libraries displaying peptides of diverse lengths and at diverse capsid positions.

Intratumoral T but not B lymphocytes are related to clinical outcome in prostate cancer.

High tissue density of FOXP3+ T cells is associated with clinical outcome in prostate cancer.

CLL B-cell receptors can recognize themselves: alternative epitopes and structural clues for autostimulatory mechanisms in CLL.

Drugs targeting integrins for cancer therapy.

In vivo near-infrared fluorescence targeting of T cells: comparison of nanobodies and conventional monoclonal antibodies.

Multidimensional scaling analysis identifies pathological and prognostically relevant profiles of circulating T-cells in chronic lymphocytic leukemia.

Next-generation sequencing of peripheral B-lineage cells pinpoints the circulating clonotypic cell pool in multiple myeloma.

Lapatinib.

Sequential neoadjuvant chemoradiotherapy (CRT) followed by curative surgery vs. primary surgery alone for resectable, non-metastasized pancreatic adenocarcinoma: NEOPA- a randomized multicenter phase III study (NCT01900327, DRKS00003893, ISRCTN82191749).