regeneration-arrayed-gold-microelectrodes-equipped-for-real-time-cell

Regeneration of Arrayed Gold Microelectrodes Equipped for a Real-Time Cell Analyzer

The label-free cell-based assay is advantageous for biochemical study because of it does not require the use of experimental animals. Due to its ability ...

Nanjing Medical University

We developed a method to regenerate arrayed gold microelectrodes equipped for a commercial label-free cell analyzer. The regeneration process includes efficient treatment of the gold surface with trypsin (0.25%, v/v) digestion, rinsing with ethanol and deionized water and spinning steps. The proposed method ensured complete regeneration and repeated usage of gold microchips up to 4 times for the real-time electric impedance measurement of anti-cancer drug cytotoxicity.

A general method to regenerate arrayed gold microelectrodes for label-free cell assay.

BiOCl-SiO₂ KIT-6 composite materials with raspberry-like structures are facilely prepared under hydrothermal conditions. The mesoporous siliceous support of SiO₂ KIT-6-incorporated BiOCl with enlarged yet refined surface morphology characterized by physiochemical methods exhibits an improved electrochemical performance. A sensitive electrochemical detection method of cadmium concentration using square wave anodic stripping voltammetry was developed based on BiOCl-SiO₂ KIT-6 composite-modified glassy carbon electrodes, which displayed wide linear ranges of 0.5 to 10 μg/L and 10 to 300 μg/L and a detection limit of 65 ng/L. The sensitive, versatile and eco-friendly sensor was successfully applied for the determination of cadmium-spiked human blood samples.

Yiyan Song

School of Public Health

Nanjing Medical University

Regeneration of Arrayed Gold Microelectrodes Equipped for a Real-Time Cell Analyzer

Yiyan Song

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Nanjing Medical University

Regeneration of Arrayed Gold Microelectrodes Equipped for a Real-Time Cell Analyzer

School of Public Health