identifying-amino-acid-overproducers-using-rare-codon-rich-markers

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers

To satisfy the ever-growing market for amino acids, high-performance production strains are needed. The amino acid overproducers are conventionally ...

beijing institute of technology

Corynebacterium glutamicum is an important industrial strain for the production of a diverse range of chemicals. Cpf1 nucleases are highly specific and programmable, with efficiencies comparable to those of Cas9. Although the Francisella novicida (Fn) CRISPR-Cpf1 system has been adapted for genome editing in C. glutamicum, the editing efficiency is currently less than 15%, due to false positives caused by the poor targeting efficiency of the crRNA.

Yunpeng Yang

Key Laboratory of Molecular Medicine and Biotherapy,
School of Life Sciences,
Key Laboratory of Molecular Medicine and Biotherapy, School of Life Sciences

beijing institute of technology

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers

Yunpeng Yang

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Key Laboratory of Molecular Medicine and Biotherapy,School of Life Sciences,Key Laboratory of Molecular Medicine and Biotherapy, School of Life Sciences

beijing institute of technology

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers

Key Laboratory of Molecular Medicine and Biotherapy,
School of Life Sciences,
Key Laboratory of Molecular Medicine and Biotherapy, School of Life Sciences