Chi Li
Department of Pharmacology and Toxicology,
Experimental Therapeutics Program,
Brown Cancer Center,
Department of Medicine,
Experimental Therapeutics Program, Brown Cancer Center
University of Louisville
Chia-Wei Liou is a Ph.D. student in the Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University in Taiwan. He received his Master degree in the Department of Physiology, College of Medicine, National Cheng Kung University (NCKU).
Chia-Wei focus on the effects of high-dietary sugar on renal function and using Drosophila as an experimental model. After he joined Dr. Wei-Li Wu's lab in NCKU, he started to be trained with the techniques in neuroscience and received the knowledge of neuroscience and gut-brain axis. His thesis during Ph.D. program is to study the effects of gut metabolites in the brain to regulate emotional behaviors in mice.
Apoptosis regulation by Bcl-x(L) modulation of mammalian inositol 1,4,5-trisphosphate receptor channel isoform gating.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2007 | Pubmed ID: 17636122
The Bax carboxy-terminal hydrophobic helix does not determine organelle-specific targeting but is essential for maintaining Bax in an inactive state and for stable mitochondrial membrane insertion.
Apoptosis : an international journal on programmed cell death Jan, 2010 | Pubmed ID: 19809877
Actinomycin D synergistically enhances the efficacy of the BH3 mimetic ABT-737 by downregulating Mcl-1 expression.
Cancer biology & therapy Nov, 2010 | Pubmed ID: 20818182
ER stress modulates cellular metabolism.
The Biochemical journal Apr, 2011 | Pubmed ID: 21241252
Distinct roles of mitochondria- and ER-localized Bcl-xL in apoptosis resistance and Ca2+ homeostasis.
Molecular biology of the cell Jul, 2012 | Pubmed ID: 22573883
Haem oxygenase-1 overexpression alters intracellular iron distribution.
The Biochemical journal Jan, 2013 | Pubmed ID: 22989377
Titanium dioxide (TiO2) nanoparticles preferentially induce cell death in transformed cells in a Bak/Bax-independent fashion.
PloS one , 2012 | Pubmed ID: 23185639
An interaction between Bcl-xL and the voltage-dependent anion channel (VDAC) promotes mitochondrial Ca2+ uptake.
The Journal of biological chemistry Jul, 2013 | Pubmed ID: 23720737
Noxa couples lysosomal membrane permeabilization and apoptosis during oxidative stress.
Free radical biology & medicine Dec, 2013 | Pubmed ID: 23770082
Prediction of peptide drift time in ion mobility mass spectrometry from sequence-based features.
BMC bioinformatics , 2013 | Pubmed ID: 23815343
Activation of the proapoptotic Bcl-2 protein Bax by a small molecule induces tumor cell apoptosis.
Molecular and cellular biology Apr, 2014 | Pubmed ID: 24421393
Pseudomonas aeruginosa homoserine lactone triggers apoptosis and Bak/Bax-independent release of mitochondrial cytochrome C in fibroblasts.
Cellular microbiology Jul, 2014 | Pubmed ID: 24438098
Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone.
The Journal of biological chemistry Mar, 2015 | Pubmed ID: 25627690
Proapoptotic activities of protein disulfide isomerase (PDI) and PDIA3 protein, a role of the Bcl-2 protein Bak.
The Journal of biological chemistry Apr, 2015 | Pubmed ID: 25697356
Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport.
Scientific reports May, 2015 | Pubmed ID: 26023881
Increased Mitochondrial Activity in Anthrax-Induced Cell Death.
Journal of cell death , 2009 | Pubmed ID: 26124679
How Heme Oxygenase-1 Prevents Heme-Induced Cell Death.
PloS one , 2015 | Pubmed ID: 26270345
Dissecting the leukemogenic potency of BCLxl.
Journal of leukemia (Los Angeles, Calif.) , 2014 | Pubmed ID: 26636115
N-(3-oxo-acyl) homoserine lactone inhibits tumor growth independent of Bcl-2 proteins.
Oncotarget Feb, 2016 | Pubmed ID: 26758417
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy Jan, 2016 | Pubmed ID: 26799652
N-(3-Oxo-acyl)-homoserine lactone induces apoptosis primarily through a mitochondrial pathway in fibroblasts.
Cellular microbiology 01, 2018 | Pubmed ID: 28876505
Vaccination with induced pluripotent stem cells confers protection against cancer.
Stem cell investigation , 2018 | Pubmed ID: 30148156
N-(3-oxo-acyl) homoserine lactone induced germ cell apoptosis and suppressed the over-activated RAS/MAPK tumorigenesis via mitochondrial-dependent ROS in C. elegans.
Apoptosis : an international journal on programmed cell death Aug, 2018 | Pubmed ID: 30171376
Exosomes from GM-CSF expressing embryonic stem cells are an effective prophylactic vaccine for cancer prevention.
Oncoimmunology , 2019 | Pubmed ID: 30723593
Regulatory Role of Immune Cell-Derived Extracellular Vesicles in Cancer: The Message Is in the Envelope.
Frontiers in immunology , 2020 | Pubmed ID: 32765528
Cancer Vaccines: Promising Therapeutics or an Unattainable Dream.
Vaccines Jun, 2021 | Pubmed ID: 34207062
Isolation of Exosome-Enriched Extracellular Vesicles Carrying Granulocyte-Macrophage Colony-Stimulating Factor from Embryonic Stem Cells
Shuhan Meng1,2,
Aaron G. Whitt1,2,3,
Allison Tu2,
John W. Eaton1,2,3,
Chi Li1,2,3,
Kavitha Yaddanapudi4,5,6
1Department of Pharmacology and Toxicology, University of Louisville,
2Experimental Therapeutics Program, Brown Cancer Center, University of Louisville,
3Department of Medicine, University of Louisville,
4Department of Surgery, University of Louisville,
5Immuno-Oncology Program, Brown Cancer Center, University of Louisville,
6Department of Microbiology and Immunology, University of Louisville
Copyright © 2025 MyJoVE Corporation. Wszelkie prawa zastrzeżone