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Cosimo Commisso

Sanford Burnham Prebys Medical Discovery Institute

NCI-designated Cancer Center

BIOGRAPHY

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PUBLICATIONS

High-content, full genome siRNA screen for regulators of oncogenic HRAS-driven macropinocytosis.

Assay and drug development technologies Sep, 2015 | Pubmed ID: 26267765

Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer.

Frontiers in endocrinology , 2017 | Pubmed ID: 29085336

Macropinocytosis Fuels Prostate Cancer.

Cancer discovery 07, 2018 | Pubmed ID: 29967075

Detection and Quantification of Macropinosomes in Pancreatic Tumors.

Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30378054

Quantitation of Macropinocytosis in Cancer Cells.

Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30725454

The pervasiveness of macropinocytosis in oncological malignancies.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences 02, 2019 | Pubmed ID: 30967003

Macropinocytosis in Cancer: A Complex Signaling Network.

Trends in cancer 06, 2019 | Pubmed ID: 31208695

EGFR-Pak Signaling Selectively Regulates Glutamine Deprivation-Induced Macropinocytosis.

Developmental cell 08, 2019 | Pubmed ID: 31257175

Golgi Acidification by NHE7 Regulates Cytosolic pH Homeostasis in Pancreatic Cancer Cells.

Cancer discovery 06, 2020 | Pubmed ID: 32200349

Metabolic regulation of EGFR effector and feedback signaling in pancreatic cancer cells requires K-Ras.

Biochemical and biophysical research communications 12, 2020 | Pubmed ID: 32972751

Rac1 and EGFR cooperate to activate Pak in response to nutrient stress.

Biochemical and biophysical research communications 12, 2020 | Pubmed ID: 32972756

Macropinocytosis in Cancer-Associated Fibroblasts Is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness.

Cancer discovery Jul, 2021 | Pubmed ID: 33653692

The Golgi as a "Proton Sink" in Cancer.

Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34055797

INSTITUTIONS

NCI-designated Cancer Center

JOVE ARTICLES

Automated Imaging and Analysis for the Quantification of Fluorescently Labeled Macropinosomes

Koen M. O. Galenkamp¹,

Cheska Marie Galapate¹,

Yijuan Zhang¹,

Cosimo Commisso¹

¹Sanford Burnham Prebys Medical Discovery Institute, NCI-designated Cancer Center

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