a-personalized-3d-printed-model-for-preoperative-evaluation-thyroid

A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery

The anatomic structure of the surgical area of thyroid cancer is complex. It is very important to comprehensively and carefully evaluate the tumor ...

Sichuan University

The present study utilized an  dual-species biofilm model and an  rat post-treatment endodontic disease (PTED) model to investigate whether co-infection of  and  would aggravate periapical lesions. The results showed that co-culturing yielded a thicker and denser biofilm more tolerant to detrimental stresses compared with the mono-species biofilm, such as a starvation-alkalinity environment, mechanical shear force and bactericidal chemicals. Consistently, co-inoculation of  and  significantly increased the extent of  periapical lesions compared with mono-species infection. Specifically, coexistence of both microorganisms increased osteoclastic bone resorption and suppressed osteoblastic bone formation. The synergistic effects also up-regulated inflammatory cytokines including  and . In summary, coexistence of  and  increased periapical lesions by enhanced biofilm virulence.

Coexistence of  and  increases biofilm virulence and periapical lesions in rats.

Artificial articular cartilage (AC) is extensively applied in the repair and regeneration of cartilage which lacks self-regeneration capacity because of its avascular and low-cellularity nature. With advances in tissue engineering, bioengineering techniques for artificial AC construction have been increasing and maturing gradually. In this review, we elaborated on the advances of biological scaffold technologies in artificial AC including freeze-drying, electrospinning, 3D bioprinting and decellularized, and scaffold-free methods such as self-assembly and cell sheet. In the following, several successful applications of artificial AC built by scaffold and scaffold-free techniques are introduced to demonstrate the clinical application value of artificial AC.

YIFei Chen

West China School/Hospital of Stomatology

Sichuan University

A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery

YIFei Chen

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Sichuan University

A Personalized 3D-Printed Model for Preoperative Evaluation in Thyroid Surgery

West China School/Hospital of Stomatology