Melissa C. Skala

Autofluorescence flow sorting of breast cancer cell metabolism.

Metabolic Imaging of Head and Neck Cancer Organoids.

Autofluorescence imaging identifies tumor cell-cycle status on a single-cell level.

Functional Optical Imaging of Primary Human Tumor Organoids: Development of a Personalized Drug Screen.

In vivo photothermal optical coherence tomography of endogenous and exogenous contrast agents in the eye.

Oxidative stress via inhibition of the mitochondrial electron transport and Nrf-2-mediated anti-oxidative response regulate the cytotoxic activity of plumbagin.

Protein-bound NAD(P)H Lifetime is Sensitive to Multiple Fates of Glucose Carbon.

Quantifying optical properties with visible and near-infrared optical coherence tomography to visualize esophageal microwave ablation zones.

Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells.

Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography.

BET inhibitors reduce cell size and induce reversible cell cycle arrest in AML.

MTORC1/2 Inhibition as a Therapeutic Strategy for Mutant Cancers.

Organotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations.

Quantitative Label-Free Imaging of 3D Vascular Networks Self-Assembled in Synthetic Hydrogels.

Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines.

Redox imaging and optical coherence tomography of the respiratory ciliated epithelium.

Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model.

Imaging intratumoral metabolic heterogeneity.

Cellular Metabolic Heterogeneity In Vivo Is Recapitulated in Tumor Organoids.

Photothermal Optical Coherence Tomography of Anti-Angiogenic Treatment in the Mouse Retina Using Gold Nanorods as Contrast Agents.

Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation.

Effects of culture method on response to EGFR therapy in head and neck squamous cell carcinoma cells.

Tumor-on-a-chip: a microfluidic model to study cell response to environmental gradients.

Classifying T cell activity in autofluorescence intensity images with convolutional neural networks.

Sample preparation strategies for high-throughput mass spectrometry imaging of primary tumor organoids.

Quantitative Spatial Analysis of Metabolic Heterogeneity Across and Tumor Models.

Development of a Microfluidic Array to Study Drug Response in Breast Cancer.

Human Tumor-Lymphatic Microfluidic Model Reveals Differential Conditioning of Lymphatic Vessels by Breast Cancer Cells.

Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications.

Label-free redox imaging of patient-derived organoids using selective plane illumination microscopy.

Metabolic Heterogeneity in Patient Tumor-Derived Organoids by Primary Site and Drug Treatment.

MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBC.

Classification of T-cell activation via autofluorescence lifetime imaging.

A bioengineered organotypic prostate model for the study of tumor microenvironment-induced immune cell activation.

Adaptable pulsatile flow generated from stem cell-derived cardiomyocytes using quantitative imaging-based signal transduction.

Autofluorescence Imaging of 3D Tumor-Macrophage Microscale Cultures Resolves Spatial and Temporal Dynamics of Macrophage Metabolism.

Microfluidic Tumor-on-a-Chip Model to Study Tumor Metabolic Vulnerability.

Carbomer-based adjuvant elicits CD8 T-cell immunity by inducing a distinct metabolic state in cross-presenting dendritic cells.

Microfluidic tumor-on-a-chip model to evaluate the role of tumor environmental stress on NK cell exhaustion.

Patient-derived cancer organoid tracking with wide-field one-photon redox imaging to assess treatment response.

The NIH Somatic Cell Genome Editing program.

Autofluorescence Imaging of Treatment Response in Neuroendocrine Tumor Organoids.

Intravital Metabolic Autofluorescence Imaging Captures Macrophage Heterogeneity Across Normal and Cancerous Tissue.

Extracellular pH affects the fluorescence lifetimes of metabolic co-factors.

Optical Coherence Tomography Angiography in the Thirteen-Lined Ground Squirrel.

Recent innovations in fluorescence lifetime imaging microscopy for biology and medicine.

Label-free imaging for quality control of cardiomyocyte differentiation.

Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography.

Maturation- and degeneration-dependent articular cartilage metabolism via optical redox ratio imaging.

Breast cancer immunotherapy: current biomarkers and the potential of assays.

Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors.

In vivo fluorescence lifetime imaging of macrophage intracellular metabolism during wound responses in zebrafish.

Technologies to Assess Drug Response and Heterogeneity in Patient-Derived Cancer Organoids.

Microphysiological model of renal cell carcinoma to inform anti-angiogenic therapy.

Impact of baseline culture conditions of cancer organoids when determining therapeutic response and tumor heterogeneity.

Innate immune cell response to host-parasite interaction in a human intestinal tissue microphysiological system.

Label-Free Imaging to Track Reprogramming of Human Somatic Cells.

Inhibition of B-cell lymphoma 2 family proteins alters optical redox ratio, mitochondrial polarization, and cell energetics independent of cell state.

autofluorescence lifetime assay of a photoreceptor stimulus response in mouse retina and human retinal organoids.

Treatment Inequity: Examining the Influence of Non-Hispanic Black Race and Ethnicity on Pancreatic Cancer Care and Survival in Wisconsin.

Prostate cancer cells demonstrate unique metabolism and substrate adaptability acutely after androgen deprivation therapy.

Touch-free optical technologies to streamline the production of T cell therapies.

Autofluorescence lifetime imaging classifies human lymphocyte activation and subtype.

Light sheet autofluorescence lifetime imaging with a single photon avalanche diode array.

Inflammatory CD4/CD8 double-positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology.

Single cell metabolic imaging of tumor and immune cells in melanoma bearing mice.

Microphysiological head and neck cancer model identifies novel role of lymphatically secreted monocyte migration inhibitory factor in cancer cell migration and metabolism.

Optical coherence tomography of human fetal membrane sub-layers during loading.

Light-sheet autofluorescence lifetime imaging with a single-photon avalanche diode array.

Microfluidic device with reconfigurable spatial temporal gradients reveals plastic astrocyte response to stroke and reperfusion.

Griddient: a microfluidic array to generate reconfigurable gradients on-demand for spatial biology applications.

Preclinical Models of Anal Cancer Combined-Modality Therapy.

Microphysiological model reveals the promise of memory-like natural killer cell immunotherapy for HIV cancer.

Label-free optical imaging and sensing for quality control of stem cell manufacturing.

Author Correction: Microphysiological model reveals the promise of memory-like natural killer cell immunotherapy for HIV cancer.

Development of a multilayer fetal membrane material model calibrated using bulge inflation mechanical tests.

Perspectives on label-free microscopy of heterogeneous and dynamic biological systems.

Autofluorescence is a biomarker of neural stem cell activation state.

Targeting DNMT3A-mediated oxidative phosphorylation to overcome ibrutinib resistance in mantle cell lymphoma.