In Vitro Cultivation Techniques for Modeling Liver Organogenesis, Building Assembloids, and Designing Synthetic Tissues using Human Cell LinesSimran Kumar 1, Jenna Venturo 1, Helly Patel 1, Lokprakash Aravindan 3, Kyle Leatt 3, Natesh Parashurama 1,2,3,4,5
1Department of Biomedical Engineering, University at Buffalo (State University of New York), 2Clinical and Translation Research Center (CTRC), University at Buffalo (State University of New York), 3Department of Chemical and Biological Engineering, University at Buffalo (State University of New York), 4Center for Cell, Gene and Tissue Engineering, University at Buffalo, State University of New York, 5Khufu Therapeutics, Inc.
Organoids revolutionize personalized tissue modeling for organ development, drug discovery, and disease research. Organoid engineering advances into creating intricate synthetic tissues. The aim is to integrate morphogenesis, assembloid technology, and biomatrices to advance tissue engineering. This protocol aids in modeling liver organogenesis and establishing guidelines for synthetic tissue construction.
