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CSIR-Central Scientific Instruments Organisation

1 ARTICLES PUBLISHED IN JoVE

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Cancer Research

Plasmonic Photothermal Cancer Therapy: Nanoparticle-embedded Tumor-tissue-mimicking Phantoms for Visualizing Photothermal Temperature Distribution
Amit Kumar Shaw *1,2, Divya Khurana *1, Sanjeev Soni 1,2
1CSIR-Central Scientific Instruments Organisation, 2Academy of Scientific and Innovative Research (AcSIR)

This article presents the protocol for preparing tumor-tissue phantoms that replicate optical properties for plasmonic photothermal therapy. It details phantom preparation, photothermal evaluations, and validation of the developed numerical model based on photothermal temperature measurements for assessing therapeutic parameters, offering an ethical, cost-effective alternative to in vivo studies for preliminary testing.

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