DURHAM VA MEDICAL CENTER
2 ARTICLES PUBLISHED IN JoVE
Neuroscience
Placement of Extracranial Stimulating Electrodes and Measurement of Cerebral Blood Flow and Intracranial Electrical Fields in Anesthetized Mice
Simone Degan 1, Yu Feng 1, Ulrike Hoffmann 2, Dennis A. Turner 1,3,4,5
1Department of Neurosurgery, Duke University Medical Center, 2Department of Anesthesiology and Pain Management, University Texas Southwestern Medical School, 3Department of Neurobiology, Duke University Medical Center, 4Department of Biomedical Engineering, Duke University, 5Research and Surgery Services, Durham VA Medical Center
We describe a protocol for assessing dose-response curves for extracranial stimulation in terms of brain electrical field measurements and a relevant biomarker-cerebral blood flow. Since this protocol involves invasive electrode placement into the brain, general anesthesia is needed, with spontaneous breathing preferred rather than controlled respirations.
Medicine
Point-of-care Ultrasound to Screen for Gastrointestinal Dysfunction: Image Acquisition and Interpretation
Lior Abramson 1,2, Jacqueline K. Olive 3,4, Brice Lefler 1,2, Lindsey Wu 1,2, Amber Bowman 1,2, Tyler Simpson 4, Cory Vatsaas 4, Mamata Yanamadala 1,2, Yuriy S. Bronshteyn 1,5
1Durham VA Medical Center, 2Department of Medicine, Duke University School of Medicine, 3Division of Cardiovascular and Thoracic Surgery, Department of Surgery, Duke University School of Medicine, 4Division of Trauma, Acute, and Critical Care Surgery, Department of Surgery, Duke University School of Medicine, 5Department of Anesthesiology, Duke University School of Medicine
Screening for gastrointestinal (GI) dysfunction using point-of-care ultrasound (POCUS) has been reported but remains underutilized. This manuscript reviews the relevant literature and describes a protocol that permits POCUS screening for dilation/dysfunction of the small bowel and/or stomach, which can arise as the final common pathway of various GI pathologies.