Alpert Medical School of Brown University

1 ARTICLES PUBLISHED IN JoVE

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Bioengineering

An Experimental System to Study Mechanotransduction in Fetal Lung Cells
Yulian Wang 1, Zheping Huang 1, Pritha S. Nayak 1, Juan Sanchez-Esteban 1
1Women & Infants Hospital of Rhode Island, Alpert Medical School of Brown University

Mechanical forces play a key role in lung development and lung injury. Here, we describe a method to isolate rodent fetal lung type II epithelial cells and fibroblasts and to expose them to mechanical stimulation using an in vitro system.

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