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Bioengineering

Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips
Richard Novak *1, Meredyth Didier *1,2, Elizabeth Calamari 1, Carlos F Ng 1, Youngjae Choe 1, Susan L Clauson 1, Bret A Nestor 1, Jefferson Puerta 1, Rachel Fleming 1, Sasan J Firoozinezhad 1, Donald E Ingber 1,3,4
1Wyss Institute for Biologically Inspired Engineering, Harvard University, 2Apple, Inc, 3Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, 4Vascular Biology Program and Department of Surgery, Boston Children's Hospital and Harvard Medical School

Here, we present a protocol that describes the fabrication of stretchable, dual channel, organ chip microfluidic cell culture devices for recapitulating organ-level functionality in vitro.

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