Reconstruction of the Blood-Brain Barrier In Vitro to Model and Therapeutically Target Neurological Disease

Please note that all translations are automatically generated. Click here for the English version.

1.8K Views

•

06:19 min

•

October 20th, 2023

DOI :

10.3791/65921-v

October 20th, 2023

•

Camille Goldman*¹^,²^,³^,⁴^,⁵, Natalie Suhy*¹^,²^,³^,⁴^,⁵, Jessica E. Schwarz¹^,²^,³^,⁴^,⁵, Emily Ruth Sartori¹^,²^,³^,⁴^,⁵, Rikki B. Rooklin¹^,²^,³^,⁴^,⁵, Braxton R. Schuldt¹^,²^,³^,⁴^,⁵, Louise A. Mesentier-Louro¹^,²^,³^,⁴^,⁵, Joel W. Blanchard¹^,²^,³^,⁴^,⁵

¹Icahn School of Medicine at Mount Sinai, ²Black Family Stem Cell Institute at Mount Sinai, ³Ronald M. Loeb Center for Alzheimer’s Disease at Mount Sinai, ⁴Friedman Brain Institute at Mount Sinai, ⁵Nash Family Department of Neuroscience at Mount Sinai

Podsumowanie

Przeglądaj więcej filmów

Blood brain Barrier

Alzheimer s Disease

Neurodegeneration

Cerebrovascular Pathologies

Induced Pluripotent Stem Cells

Therapeutic Strategies

BBB Dysfunction

Human Brain Tissue Model

Amyloid Pathology

Personalized Therapy

Genetic Background

Cerebral Amyloid Angiopathy

Rozdziały w tym wideo

0:00

Introduction

2:07

Preparing Cells to Assemble a 3D Human‐Stem‐Cell‐Derived In Vitro Blood Brain Barrier

4:11

Constructing the 3D Human‐Stem‐Cell‐Derived In Vitro Blood Brain Barrier

Powiązane Filmy

article

Predicting In Vivo Payloads Delivery using a Blood-brain Tumor-barrier in a Dish

9.0K Views

article

Improved Method for the Preparation of a Human Cell-based, Contact Model of the Blood-Brain Barrier

16.2K Views

article

Rat Model of Blood-brain Barrier Disruption to Allow Targeted Neurovascular Therapeutics

19.4K Views

article

Setting-up an In Vitro Model of Rat Blood-brain Barrier (BBB): A Focus on BBB Impermeability and Receptor-mediated Transport

42.3K Views

article

Generation of a Human iPSC-Based Blood-Brain Barrier Chip

12.3K Views

article

A Triple Primary Cell Culture Model of the Human Blood-Brain Barrier for Studying Ischemic Stroke In Vitro

3.8K Views

article

An In Vitro Model of the Blood-brain Barrier Using Impedance Spectroscopy: A Focus on T Cell-endothelial Cell Interaction

11.2K Views

article

In Vitro Assays to Assess Blood-brain Barrier Mesh-like Vessel Formation and Disruption

8.4K Views

article

Improved Method for the Establishment of an In Vitro Blood-Brain Barrier Model Based on Porcine Brain Endothelial Cells

14.7K Views

article

A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain

8.6K Views

Copyright © 2025 MyJoVE Corporation. Wszelkie prawa zastrzeżone