<h2 class="jove_title">
	<a href="https://www.jove.com/video/50423">Microwave Photonics Systems Based on Whispering-gallery-mode Resonators</a></h2>
Aur&#233;lien Coillet, R&#233;mi Henriet, Kien Phan Huy, Maxime Jacquot, Luca Furfaro, Irina Balakireva, Laurent Larger, Yanne K. Chembo
Optics Department, FEMTO-ST Institute
The customized techniques developed in our lab to build microwave photonics systems based on ultra-high Q whispering gallery mode resonators are presented. The protocols to obtain and characterize these resonators are detailed, and an explanation of some of their applications in microwave photonics is given.
<h2 class="jove_title">
	<a href="https://www.jove.com/video/50460">Tissue Engineering of a Human 3D In vitro Tumor Test System</a></h2>
Corinna Moll*, Jenny Reboredo*, Thomas Schwarz, Antje Appelt, Sebastian Sch&#252;rlein, Heike Walles, Sarah Nietzer
Department of Tissue Engineering and Regenerative Medicine, University Hospital W&#252;rzburg
Methods to create human 3D tumor tissues as test systems are described. These technologies are based on a decellularized Biological Vascularized Scaffold (BioVaSc), primary human cells and a tumor cell line, which can be cultured under static as well as under dynamic conditions in a flow bioreactor.
<h2 class="jove_title">
	<a href="https://www.jove.com/video/50538">An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization</a></h2>
David Dunston, Sarah Ashby*, Kurt Krosnowski*, Tatsuya Ogura, Weihong Lin
Biological Sciences, University of Maryland Baltimore County
<h2 class="jove_title">
	<a href="https://www.jove.com/video/50550">Obtaining Specimens with Slowed, Accelerated and Reversed Aging in the Honey Bee Model</a></h2>
Daniel M&#252;nch1, Nicholas Baker2, Erik M.K. Rasmussen1, Ashish K. Shah1, Claus D. Kreibich1, Lars E. Heidem1, Gro V. Amdam1,2
1Department of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, 2School of Life Sciences, Arizona State University
In honey bee workers, aging depends on social behaviors rather than on chronological age. Here we show how worker-types with very different aging patterns can be obtained and analyzed for cellular senescence.

No conflicts of interest declared.

august 2013: this month in jove

Here&#8217;s a look at what&#8217;s coming up in the <a href="http://www.jove.com/archive/78">August 2013 issue</a> of JoVE: The Journal of Visualized Experiments.
Honey is an age-old anti-aging product; according to legend, Cleopatra, the Queen of the Nile, bathed in honey to preserve her ageless beauty. But did you know that honeybees themselves might hold the secret to slowing or even reversing aging? The honeybee is an established model for studying how social and environmental factors can affect the aging process. Nurse bees, which stay in the hive to tend the growing larvae, age more slowly than forager bees, which venture out to collect nectar and pollen. <a href="http://www.jove.com/video/50550">M&#252;nch et al.</a> expand classical experimental paradigms with three new techniques for studying aging in honeybees: distinguishing chronological aging from work-induced senescence, reverting forager bees into nurse bees by taking them to a new hive, and quantifying aging by measuring lipofuscin (a known biomarker of cellular senescence).
It smells like smoke over in the <a href="http://www.jove.com/behavior">JoVE Behavior</a> section, where we feature a method for studying the brain&#8217;s response to cigarette smoking. <a href="http://www.jove.com/video/50358">Morris et al.</a> use positron emission tomography (PET) to non-invasively image the dopaminergic system during smoking. They also make dopamine movies to illustrate how smoking causes dopamine levels to fluctuate in the striatal area of the brain. Because the rise and fall of striatal dopamine levels contribute to addiction and withdrawal, this is a powerful technique for studying the addictive effects of smoking.
In <a href="http://www.jove.com/ap">JoVE Applied Physics</a>, we feature an article in the field of microwave photonics, which studies the interaction between microwaves and optical waves. <a href="http://www.jove.com/video/50423">Coillet et al.</a> build microwave photonics systems based on whispering gallery modes (WGMs), which are waves that can travel around a concave surface. To make the resonator, Coillet et al. grind down a commercially available crystalline optical window, polish it with extremely fine particles, and verify its smoothness using interferometric measurements. Then, they draw a fiber taper, which couples light in the resonator. Finally, they show how to excite a WGM. This is a promising technology with many potential applications in aerospace, telecommunications, and other areas.
In <a href="http://www.jove.com/bioengineering">JoVE Bioengineering</a>, <a href="http://www.jove.com/video/50460">Moll et al.</a> build upon classic two-dimensional cell culture with an engineered three-dimensional tumor test system. In this biological vascularized scaffold, a metal insert containing decellularized small intestinal submucosa serves as a scaffold for culturing cancer cells or other cell types. These than be grown statically or as a dynamic culture in a flow bioreactor, which exposes cells to shear stress. This allows a lifelike model for studying tumor development and potential treatments.
 You&#8217;ve just had a sneak peek of a few highlights from the <a href="http://www.jove.com/archive/78">August 2013 issue</a> of JoVE. Visit the website to see the full-length articles, plus many more, in <a href="http://www.jove.com">JoVE: The Journal of Visualized Experiments</a>.

Watch this Scientific Journal Video about August 2013: This Month in JoVE at JoVE.com

August 2013: This Month in JoVE

Here&#8217;s a look at what&#8217;s coming up in the <a href="http://www.jove.com/archive/78">August 2013 issue</a> of JoVE: The Journal of Visualized Experiments.

Here&#8217;s a look at what&#8217;s coming up in the August 2013 issue of JoVE: The Journal of Visualized Experiments.
Honey is an age-old anti-aging ...

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6.4K Views.  Massachusetts Eye and Ear. Here’s a look at what’s coming up in the August 2013 issue of JoVE: The Journal of Visualized Experiments.

Video: August 2013: This Month in JoVE

2012: A Year In Review

Here's a look at some of the milestones and highlights of the year 2012 in Journal of Visualized Experiments (JoVE).
At the start of 2012, JoVE reached a major milestone by publishing our 1500th article. In this publication, in JoVE Bioengineering, Yu et al. described a method for analyzing the free radical composition of cigarette smoke. This method simulated cigarette puffing with a single-port smoking device, and combined it with electron spin resonance (ESR) spectroscopy to measure the degree to which antioxidant compounds can scavenge free radicals in cigarette smoke. A possible outcome of this research is the creation of less harmful cigarettes.
JoVE Bioengineering also contained the most-viewed article of 2012. Owczarczak et al. described a method for hacking a standard inkjet printer, loading ink cartridges with a cell-suspension "bioink," and printing lines of live cells onto glass slides. The thermal inkjet printing process creates temporary pores in the cell membrane, visualized by the incorporation of fluorescently labeled actin monomers. This concept, called "bioprinting," has many potential applications in cell and tissue engineering.
Also in 2012, JoVE Bioengineering featured a protocol by Hsia et al. for isolating and purifying spider silk protein, spinning it into fibers, and assessing the fiber strength. This protocol for laboratory-scale production of spider silk, which is stronger than tensile steel, can potentially be extended to large-scale manufacturing.
In JoVE Clinical and Translational Medicine, we featured a number of articles related to stroke, one of which. In one article, M&ouml;bius-Winkler et al. demonstrated placement of the WATCHMAN left atrial appendage occlusion device from Boston Scientific. This device is designed to prevent strokes by trapping clots within the left atrial appendage of the heart before they exit. Our authors demonstrated how to insert the guide wire through the femoral artery into the heart, advance the device into the left atrium, and deploy the device in the left atrial appendage.
Another article focused on stroke, Hamel et al. described the use of a driving simulator to study how patients compensate for visual field defects following stroke. By analyzing the compensatory gaze behavior of patients as they navigated through virtual driving courses with varying degrees of complexity, our authors see great potential for the use of driving simulators in stroke rehabilitation.
In JoVE Immunology and Infection, we published an article by Keyel et al. describing the real-time kinetics of immune cell responses to bacterial toxins using live cell microscopy. Combined with high-speed 3D confocal microscopy, this technique can also visualize the cellular repair response.
Also in JoVE Immunology and Infection, we featured an article by Yap et al. describing methods for diagnosing helminth infections in children. Helminths are parasitic worms that can infect the intestinal tract of humans and animals, and may be distinguished based on their morphology. The same article demonstrated how to measure the impact of helminth infections on physical fitness in children, which is a measure of overall health.
In JoVE Neuroscience, we featured a method by Hoffmann et al., who used tiny headphones to alter the auditory feedback in songbirds, and analyzed the computational and neurophysiological basis of vocal learning in birds when they adjust their singing in response to altered acoustic signals.
Also in JoVE Neuroscience, we moved from birds to bees with a method that assesses associative and non-associative tactile learning in honeybees. This method, by Mujagi&#263; et al., allowed bees to scan different metal surfaces with their antennae, then conditioned them to expect sugar water when their antennae touched particular surfaces, and analyzed the corresponding changes in antennal movement.
In 2012, we launched a brand-new section: JoVE Applied Physics, which features articles on subjects ranging from plasma physics to material science. The Applied Physics section also contained JoVE's 2000th video article, filmed in a synchrotron radiation facility, where Borisenko et al. showed how to determine the electronic structure of complex materials using angle-resolved photoemission spectroscopy.
In the JoVE General section, we published an article by Artioli et al. demonstrating the use of a portable gas analyzer to measure oxygen consumption during complex exercise - such as judo. By analyzing oxygen consumption and collecting blood for measuring plasma lactate concentration, this method can determine the relative contributions of different energy systems to specific aspects of complex exercise.
Finally, JoVE followed Dolhi et al. to a permanently ice-covered saline lake in Antarctica. There, scientists drilled through the ice to study single-celled microorganisms called protists that live in the harsh conditions of Antarctica.
This Year in Review was just a brief glimpse of a few of over 600 video articles that JoVE offered in 2012. Browse the JoVE archives to see thousands of other videos, and stay tuned for what's coming up this year in JoVE: The Journal of Visualized Experiments.

Here's a look at some of the milestones and highlights of the year 2012 in Journal of Visualized Experiments (JoVE).

 
 
Here's a look at some of the milestones and highlights of the year 2012 in Journal of Visualized Experiments (JoVE).
At the start of 2012, JoVE ...