Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy

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10.5K Views

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05:05 min

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November 29th, 2018

DOI :

10.3791/57849-v

November 29th, 2018

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Eriko Katsuta¹, Masanori Oshi¹, Omar M. Rashid²^,³^,⁴^,⁵, Kazuaki Takabe¹^,⁶^,⁷^,⁸^,⁹^,¹⁰

¹Breast Surgery, Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, ²Holy Cross Hospital Michael and Dianne Bienes Comprehensive Cancer Center, ³Department of Surgery, Massachusetts General Hospital, ⁴Department of Surgery, University of Miami Miller School of Medicine, ⁵Department of Surgery, Nova Southeastern University School of Medicine, ⁶Department of Surgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, ⁷Department of Breast Surgery and Oncology, Tokyo Medical University, ⁸Department of Surgery, Yokohama City University, ⁹Department of Surgery, Niigata University Graduate School of Medical and Dental Sciences, ¹⁰Department of Surgery, Fukushima Medical University

Podsumowanie

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Keywords Murine Orthotopic Metastatic Breast Cancer Model

Murine Radical Mastectomy

Breast Cancer Progression

Mouse Breast Cancer Model

Tumorigenesis

Local Recurrence

Mammary Fat Pad

Cancer Cell Inoculation

Lung Metastasis Quantification

D Luciferin

Rozdziały w tym wideo

0:04

Title

0:38

Cancer Cell Inoculation

1:55

Mastectomy and Lung Metastasis Tumor Burden Quantification

3:48

Results: Representative Primary and Metastasized Tumor Burden Analyses

4:41

Conclusion

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