Simultaneous Focused Ultrasound Neuromodulation and Fiber Photometry Recording in Free-Moving Mouse

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742 Views

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08:38 min

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September 6th, 2024

DOI :

10.3791/67090-v

September 6th, 2024

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Na Li*¹^,², Zihao Chen*¹^,³, Jiejun Zhu¹, Hanming Zheng¹^,⁴, Jinzhao Xia¹^,⁵, Zhen Yuan⁴, Chunlong Fei², Lei Sun³, Zhihai Qiu¹

¹Guangdong Institute of Intelligence Science and Technology, ²School of Microelectronics, Xidian University, ³Department of Biomedical Engineering, The Hong Kong Polytechnic University, ⁴Centre for Cognitive and Brain Sciences and Ministry of Education Frontiers Science Center for Precision Oncology, University of Macau, ⁵Deep Brain Technology Co., Ltd

Podsumowanie

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Simultaneous Focused Ultrasound Neuromodulation

Fiber Photometry

GCaMP6s Fluorescence

Neuronal Circuits

Non invasive Perturbation

Brain Function Monitoring

Deep Brain Regions

Closed loop Feedback

Neural Circuitry Responses

Thy1 GCaMP6s Mice

Anterior Thalamic Nucleus

Optical Recording

Biomedical Ultrasound

Rozdziały w tym wideo

0:00

Introduction

1:50

Transducer Preparation for Non-Invasive Perturbation of Neuronal Circuits at Deep Brain Regions

3:02

Setting up the Reporting Parameters for Focused Ultrasound Neuromodulation

4:40

Recording the Neuroactivity in the Anterior Thalamic Nucleus During Focused Ultrasound Neuromodulation in Freely Moving Mice

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