Small Molecule Pharmaceutical Sciences
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Photo-cross-linking of type I collagen gels in the presence of smooth muscle cells: mechanical properties, cell viability, and function.
Biomacromolecules Jul-Aug, 2003 | Pubmed ID: 12857069
Viscoelastic and mechanical behavior of recombinant protein elastomers.
Biomaterials Aug, 2005 | Pubmed ID: 15763249
Alterations in physical cross-linking modulate mechanical properties of two-phase protein polymer networks.
Biomacromolecules Nov-Dec, 2005 | Pubmed ID: 16283724
Quantification of compaction-induced crystallinity reduction of a pharmaceutical solid using 19F solid-state NMR and powder X-ray diffraction.
Drug development and industrial pharmacy Aug, 2009 | Pubmed ID: 19360510
Manufacture of pharmaceutical co-crystals using twin screw extrusion: a solvent-less and scalable process.
Journal of pharmaceutical sciences Apr, 2010 | Pubmed ID: 19774652
Fast surface crystallization of amorphous griseofulvin below T g.
Pharmaceutical research Aug, 2010 | Pubmed ID: 20414704
Selective and potent Raf inhibitors paradoxically stimulate normal cell proliferation and tumor growth.
Molecular cancer therapeutics Aug, 2010 | Pubmed ID: 20663930
Manufacture and performance evaluation of a stable amorphous complex of an acidic drug molecule and Neusilin.
Journal of pharmaceutical sciences Aug, 2011 | Pubmed ID: 21520086
High-throughput 96-well solvent mediated sonic blending synthesis and on-plate solid/solution stability characterization of pharmaceutical cocrystals.
International journal of pharmaceutics Jan, 2013 | Pubmed ID: 23178596
Crystal structure study and investigation of solid-state cyclization for AMG 222, a channel hydrate.
International journal of pharmaceutics Jan, 2013 | Pubmed ID: 23182974
Effect of pH and excipients on structure, dynamics, and long-term stability of a model IgG1 monoclonal antibody upon freeze-drying.
Pharmaceutical research Apr, 2013 | Pubmed ID: 23184227
Application of twin screw extrusion in the manufacture of cocrystals, part I: four case studies.
Pharmaceutics Aug, 2011 | Pubmed ID: 24310598
Structural studies of a non-stoichiometric channel hydrate using high resolution X-ray powder diffraction, solid-state nuclear magnetic resonance, and moisture sorption methods.
Journal of pharmaceutical sciences Sep, 2014 | Pubmed ID: 24470123
Sorbitol crystallization-induced aggregation in frozen mAb formulations.
Journal of pharmaceutical sciences Feb, 2015 | Pubmed ID: 25219372
Application of twin screw extrusion to the manufacture of cocrystals: scale-up of AMG 517-sorbic acid cocrystal production.
Faraday discussions , 2014 | Pubmed ID: 25406487
Amorphous solid dispersions: a robust platform to address bioavailability challenges.
Therapeutic delivery Feb, 2015 | Pubmed ID: 25690090
Application of (19) F time-domain NMR to measure content in fluorine-containing drug products.
Magnetic resonance in chemistry : MRC Jun, 2016 | Pubmed ID: 25773191
Conformational isomerism in solid state of AMG 853--structure studies using solid-state nuclear magnetic resonance and X-ray diffraction.
Journal of pharmaceutical sciences Jul, 2015 | Pubmed ID: 25912152
Investigation of Phase Mixing in Amorphous Solid Dispersions of AMG 517 in HPMC-AS Using DSC, Solid-State NMR, and Solution Calorimetry.
Molecular pharmaceutics Nov, 2015 | Pubmed ID: 26457879
A rational approach towards development of amorphous solid dispersions: Experimental and computational techniques.
International journal of pharmaceutics Mar, 2017 | Pubmed ID: 28063904
Control Strategies for Drug Product Continuous Direct Compression-State of Control, Product Collection Strategies, and Startup/Shutdown Operations for the Production of Clinical Trial Materials and Commercial Products.
Journal of pharmaceutical sciences Apr, 2017 | Pubmed ID: 28069357
Humidity induced phase transformation of poloxamer 188 and its effect on physical stability of amorphous solid dispersion of AMG 579, a PDE10A inhibitor.
International journal of pharmaceutics Apr, 2017 | Pubmed ID: 28163226
High-throughput screening and scale-up of cocrystals using resonant acoustic mixing.
International journal of pharmaceutics Apr, 2017 | Pubmed ID: 28229947
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