Department of the Control of Genetic Processes,
Institute of Gene Biology
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P element-mediated duplications of genomic regions in Drosophila melanogaster.
Chromosoma Jul, 2002 | Pubmed ID: 12111335
The su(Hw) insulator can disrupt enhancer-promoter interactions when located more than 20 kilobases away from the Drosophila achaete-scute complex.
Molecular and cellular biology May, 1999 | Pubmed ID: 10207068
TAFII40 protein is encoded by the e(y)1 gene: biological consequences of mutations.
Molecular and cellular biology May, 1999 | Pubmed ID: 10207100
Attachment of HeT-A sequences to chromosomal termini in Drosophila melanogaster may occur by different mechanisms.
Molecular and cellular biology Oct, 2000 | Pubmed ID: 11003659
The novel transcription factor e(y)2 interacts with TAF(II)40 and potentiates transcription activation on chromatin templates.
Molecular and cellular biology Aug, 2001 | Pubmed ID: 11438676
Heterochromatin protein 1 is involved in control of telomere elongation in Drosophila melanogaster.
Molecular and cellular biology May, 2002 | Pubmed ID: 11940677
The gypsy insulators flanking yellow enhancers do not form a separate transcriptional domain in Drosophila melanogaster: the enhancers can activate an isolated yellow promoter.
Genetics Apr, 2002 | Pubmed ID: 11973309
Enhancer of terminal gene conversion, a new mutation in Drosophila melanogaster that induces telomere elongation by gene conversion.
Genetics Nov, 2002 | Pubmed ID: 12454074
Transvection at the end of the truncated chromosome in Drosophila melanogaster.
Genetics Apr, 2003 | Pubmed ID: 12702682
An endogenous Su(Hw) insulator separates the yellow gene from the Achaete-scute gene complex in Drosophila.
Development (Cambridge, England) Jul, 2003 | Pubmed ID: 12783795
The Mod(mdg4) component of the Su(Hw) insulator inserted in the P transposon can repress its mobility in Drosophila melanogaster.
Genetics Jul, 2004 | Pubmed ID: 15280241
Interaction between the GAGA factor and Mod(mdg4) proteins promotes insulator bypass in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2004 | Pubmed ID: 15465920
Drosophila Su(Hw) insulator can stimulate transcription of a weakened yellow promoter over a distance.
Genetics Jul, 2005 | Pubmed ID: 15520254
A novel multidomain transcription coactivator SAYP can also repress transcription in heterochromatin.
The EMBO journal Jan, 2005 | Pubmed ID: 15616585
The Ku protein complex is involved in length regulation of Drosophila telomeres.
Genetics May, 2005 | Pubmed ID: 15781709
The Mcp element from the bithorax complex contains an insulator that is capable of pairwise interactions and can facilitate enhancer-promoter communication.
Molecular and cellular biology May, 2005 | Pubmed ID: 15831473
Drosophila telomeres: the non-telomerase alternative.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology , 2005 | Pubmed ID: 16132809
Pairing between gypsy insulators facilitates the enhancer action in trans throughout the Drosophila genome.
Molecular and cellular biology Nov, 2005 | Pubmed ID: 16227580
Handling three regulatory elements in one transgene: combined use of cre-lox, FLP-FRT, and I-Scel recombination systems.
BioTechniques Dec, 2005 | Pubmed ID: 16382906
Transposition of Regulatory Elements by P-Element-Mediated Rearrangements in Drosophila melanogaster.
Genetics Apr, 2006 | Pubmed ID: 16387869
Study of long-distance functional interactions between Su(Hw) insulators that can regulate enhancer-promoter communication in Drosophila melanogaster.
Molecular and cellular biology Feb, 2006 | Pubmed ID: 16428433
Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline.
Genes & development Feb, 2006 | Pubmed ID: 16452506
Two isoforms of Drosophila TRF2 are involved in embryonic development, premeiotic chromatin condensation, and proper differentiation of germ cells of both sexes.
Molecular and cellular biology Oct, 2006 | Pubmed ID: 17015475
Integrity of the Mod(mdg4)-67.2 BTB domain is critical to insulator function in Drosophila melanogaster.
Molecular and cellular biology Feb, 2007 | Pubmed ID: 17101769
Study of the functional interaction between Mcp insulators from the Drosophila bithorax complex: effects of insulator pairing on enhancer-promoter communication.
Molecular and cellular biology Apr, 2007 | Pubmed ID: 17283051
Evolutionarily conserved E(y)2/Sus1 protein is essential for the barrier activity of Su(Hw)-dependent insulators in Drosophila.
Molecular cell Jul, 2007 | Pubmed ID: 17643381
Long-distance interactions between regulatory elements are suppressed at the end of a terminally deficient chromosome in Drosophila melanogaster.
Chromosoma Feb, 2008 | Pubmed ID: 17876596
Characterization of Drosophila telomeric retroelement TAHRE: transcription, transpositions, and RNAi-based regulation of expression.
Molecular biology and evolution Nov, 2007 | Pubmed ID: 17890237
New properties of Drosophila fab-7 insulator.
Genetics Sep, 2007 | Pubmed ID: 17890362
Drosophila gypsy insulator and yellow enhancers regulate activity of yellow promoter through the same regulatory element.
Chromosoma Apr, 2008 | Pubmed ID: 17994318
Red flag on the white reporter: a versatile insulator abuts the white gene in Drosophila and is omnipresent in mini-white constructs.
Nucleic acids research Feb, 2008 | Pubmed ID: 18086699
'Insulator bodies' are aggregates of proteins but not of insulators.
EMBO reports May, 2008 | Pubmed ID: 18369369
Functional interaction between the Fab-7 and Fab-8 boundaries and the upstream promoter region in the Drosophila Abd-B gene.
Molecular and cellular biology Jun, 2008 | Pubmed ID: 18426914
Enhancer-promoter communication is regulated by insulator pairing in a Drosophila model bigenic locus.
Molecular and cellular biology Sep, 2008 | Pubmed ID: 18573869
Orientation-dependent interaction between Drosophila insulators is a property of this class of regulatory elements.
Nucleic acids research Dec, 2008 | Pubmed ID: 18987002
Zeste can facilitate long-range enhancer-promoter communication and insulator bypass in Drosophila melanogaster.
Chromosoma Oct, 2009 | Pubmed ID: 19578867
Drosophila mini-white model system: new insights into positive position effects and the role of transcriptional terminators and gypsy insulator in transgene shielding.
Nucleic acids research Jan, 2010 | Pubmed ID: 19854952
E(y)2/Sus1 is required for blocking PRE silencing by the Wari insulator in Drosophila melanogaster.
Chromosoma Jun, 2010 | Pubmed ID: 20082086
Interaction between a pair of gypsy insulators or between heterologous gypsy and Wari insulators modulates Flp site-specific recombination in Drosophila melanogaster.
Chromosoma Aug, 2010 | Pubmed ID: 20354861
Insulators, not Polycomb response elements, are required for long-range interactions between Polycomb targets in Drosophila melanogaster.
Molecular and cellular biology Feb, 2011 | Pubmed ID: 21135119
Selective interactions of boundaries with upstream region of Abd-B promoter in Drosophila bithorax complex and role of dCTCF in this process.
Nucleic acids research Apr, 2011 | Pubmed ID: 21149269
Drosophila BTB/POZ domains of "ttk group" can form multimers and selectively interact with each other.
Journal of molecular biology Sep, 2011 | Pubmed ID: 21821048
Insulators form gene loops by interacting with promoters in Drosophila.
Development (Cambridge, England) Sep, 2011 | Pubmed ID: 21862564
SUMO conjugation is required for the assembly of Drosophila Su(Hw) and Mod(mdg4) into insulator bodies that facilitate insulator complex formation.
Journal of cell science Apr, 2012 | Pubmed ID: 22375064
Insulator protein Su(Hw) recruits SAGA and Brahma complexes and constitutes part of Origin Recognition Complex-binding sites in the Drosophila genome.
Nucleic acids research Jun, 2013 | Pubmed ID: 23609538
New properties of Drosophila scs and scs' insulators.
PloS one , 2013 | Pubmed ID: 23638134
Effective blocking of the white enhancer requires cooperation between two main mechanisms suggested for the insulator function.
PLoS genetics , 2013 | Pubmed ID: 23861668
Chromatin insulators and long-distance interactions in Drosophila.
FEBS letters Jan, 2014 | Pubmed ID: 24211836
Making connections: insulators organize eukaryotic chromosomes into independent cis-regulatory networks.
BioEssays : news and reviews in molecular, cellular and developmental biology Feb, 2014 | Pubmed ID: 24277632
Transcription through enhancers suppresses their activity in Drosophila.
Epigenetics & chromatin Sep, 2013 | Pubmed ID: 24279291
Mechanisms and proteins involved in long-distance interactions.
Frontiers in genetics , 2014 | Pubmed ID: 24600469
Highly conserved ENY2/Sus1 protein binds to Drosophila CTCF and is required for barrier activity.
Epigenetics Sep, 2014 | Pubmed ID: 25147918
Two new insulator proteins, Pita and ZIPIC, target CP190 to chromatin.
Genome research Jan, 2015 | Pubmed ID: 25342723
Eukaryotic enhancers: common features, regulation, and participation in diseases.
Cellular and molecular life sciences : CMLS Jun, 2015 | Pubmed ID: 25715743
The boundary paradox in the Bithorax complex.
Mechanisms of development Nov, 2015 | Pubmed ID: 26215349
Functional role of dimerization and CP190 interacting domains of CTCF protein in Drosophila melanogaster.
BMC biology Aug, 2015 | Pubmed ID: 26248466
EAST Organizes Drosophila Insulator Proteins in the Interchromosomal Nuclear Compartment and Modulates CP190 Binding to Chromatin.
PloS one , 2015 | Pubmed ID: 26489095
Transcriptional read-through is not sufficient to induce an epigenetic switch in the silencing activity of Polycomb response elements.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2015 | Pubmed ID: 26504232
EAST affects the activity of Su(Hw) insulators by two different mechanisms in Drosophila melanogaster.
Chromosoma Mar, 2017 | Pubmed ID: 27136940
Architectural proteins Pita, Zw5,and ZIPIC contain homodimerization domain and support specific long-range interactions in Drosophila.
Nucleic acids research Sep, 2016 | Pubmed ID: 27137890
Transvection in Drosophila: trans-interaction between yellow enhancers and promoter is strongly suppressed by a cis-promoter only in certain genomic regions.
Chromosoma Jun, 2017 | Pubmed ID: 27300555
Functional Dissection of the Blocking and Bypass Activities of the Fab-8 Boundary in the Drosophila Bithorax Complex.
PLoS genetics 07, 2016 | Pubmed ID: 27428541
Large-scale ATP-independent nucleosome unfolding by a histone chaperone.
Nature structural & molecular biology Dec, 2016 | Pubmed ID: 27820806
Boundaries of loop domains (insulators): Determinants of chromosome form and function in multicellular eukaryotes.
BioEssays : news and reviews in molecular, cellular and developmental biology Mar, 2017 | Pubmed ID: 28133765
The GAGA factor regulatory network: Identification of GAGA factor associated proteins.
PloS one , 2017 | Pubmed ID: 28296955
Architectural protein Pita cooperates with dCTCF in organization of functional boundaries in Bithorax complex.
Development (Cambridge, England) Jul, 2017 | Pubmed ID: 28619827
Presenilin-1 Delta E9 Mutant Induces STIM1-Driven Store-Operated Calcium Channel Hyperactivation in Hippocampal Neurons.
Molecular neurobiology Jun, 2018 | Pubmed ID: 28707074
Interactions between BTB domain of CP190 and two adjacent regions in Su(Hw) are required for the insulator complex formation.
Chromosoma Mar, 2018 | Pubmed ID: 28939920
Multiple interactions are involved in a highly specific association of the Mod(mdg4)-67.2 isoform with the Su(Hw) sites in .
Open biology Oct, 2017 | Pubmed ID: 29021216
Opbp is a new architectural/insulator protein required for ribosomal gene expression.
Nucleic acids research Dec, 2017 | Pubmed ID: 29036346
Role of Su(Hw) zinc finger 10 and interaction with CP190 and Mod(mdg4) proteins in recruiting the Su(Hw) complex to chromatin sites in Drosophila.
PloS one , 2018 | Pubmed ID: 29474480
The BEN Domain Protein Insensitive Binds to the Chromatin Boundary To Establish Proper Segmental Identity in .
Genetics Oct, 2018 | Pubmed ID: 30082280
Conserved sequences in the Drosophila mod(mdg4) intron promote poly(A)-independent transcription termination and trans-splicing.
Nucleic acids research Nov, 2018 | Pubmed ID: 30102331
The bithorax complex iab-7 Polycomb response element has a novel role in the functioning of the Fab-7 chromatin boundary.
PLoS genetics Aug, 2018 | Pubmed ID: 30110328
Boundaries mediate long-distance interactions between enhancers and promoters in the Drosophila Bithorax complex.
PLoS genetics Dec, 2018 | Pubmed ID: 30540750
Functional dissection of the developmentally restricted BEN domain chromatin boundary factor Insensitive.
Epigenetics & chromatin Jan, 2019 | Pubmed ID: 30602385
Transcription termination sequences support the expression of transgene product secreted with milk.
Transgenic research Aug, 2019 | Pubmed ID: 30919251
The same domain of Su(Hw) is required for enhancer blocking and direct promoter repression.
Scientific reports Mar, 2019 | Pubmed ID: 30926937
Removal of extra sequences with I-SceI in combination with CRISPR/Cas9 technique for precise gene editing in Drosophila.
BioTechniques Apr, 2019 | Pubmed ID: 30987444
Complete reconstitution of bypass and blocking functions in a minimal artificial insulator from complex.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2019 | Pubmed ID: 31209019
The simultaneous interaction of MSL2 with CLAMP and DNA provides redundancy in the initiation of dosage compensation in males.
Development (Cambridge, England) Aug, 2019 | Pubmed ID: 31320325
Distinct Elements Confer the Blocking and Bypass Functions of the Bithorax Boundary.
Genetics Nov, 2019 | Pubmed ID: 31551239
Small Drosophila zinc finger C2H2 protein with an N-terminal zinc finger-associated domain demonstrates the architecture functions.
Biochimica et biophysica acta. Gene regulatory mechanisms Jan, 2020 | Pubmed ID: 31706027
HIPP1 stabilizes the interaction between CP190 and Su(Hw) in the Drosophila insulator complex.
Scientific reports Dec, 2019 | Pubmed ID: 31836797
N-terminal domain of the architectural protein CTCF has similar structural organization and ability to self-association in bilaterian organisms.
Scientific reports Feb, 2020 | Pubmed ID: 32060375
The insulator functions of the polydactyl C2H2 zinc finger protein CTCF: Necessity versus sufficiency.
Science advances Mar, 2020 | Pubmed ID: 32232161
Mechanisms of Enhancer-Promoter Interactions in Higher Eukaryotes.
International journal of molecular sciences Jan, 2021 | Pubmed ID: 33445415
Mapping of functional elements of the Fab-6 boundary involved in the regulation of the Abd-B hox gene in Drosophila melanogaster.
Scientific reports Feb, 2021 | Pubmed ID: 33603202
A Non-stop identity complex (NIC) supervises enterocyte identity and protects from premature aging.
eLife Feb, 2021 | Pubmed ID: 33629655
Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila.
Nucleic acids research Feb, 2021 | Pubmed ID: 33638995
Mechanism and functional role of the interaction between CP190 and the architectural protein Pita in Drosophila melanogaster.
Epigenetics & chromatin Mar, 2021 | Pubmed ID: 33752739
Boundaries potentiate polycomb response element-mediated silencing.
BMC biology Jun, 2021 | Pubmed ID: 34078365
Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types.
Cancers Jun, 2021 | Pubmed ID: 34202528
Drosophila architectural protein CTCF is not essential for fly survival and is able to function independently of CP190.
Biochimica et biophysica acta. Gene regulatory mechanisms Oct, 2021 | Pubmed ID: 34311130
Redundant enhancers in the iab-5 domain cooperatively activate Abd-B in the A5 and A6 abdominal segments of Drosophila.
Development (Cambridge, England) Oct, 2021 | Pubmed ID: 34473267
Mechanisms of CP190 Interaction with Architectural Proteins in Drosophila Melanogaster.
International journal of molecular sciences Nov, 2021 | Pubmed ID: 34830280
Dimerization Activity of a Disordered N-Terminal Domain from CLAMP Protein.
International journal of molecular sciences Mar, 2022 | Pubmed ID: 35409222
Structural insights into highly similar spatial organization of zinc-finger associated domains with a very low sequence similarity.
Structure (London, England : 1993) Jul, 2022 | Pubmed ID: 35580610
Comparative interactome analysis of the PRE DNA-binding factors: purification of the Combgap-, Zeste-, Psq-, and Adf1-associated proteins.
Cellular and molecular life sciences : CMLS Jun, 2022 | Pubmed ID: 35676368
Structure of the DNMT3B ADD domain suggests the absence of a DNMT3A-like autoinhibitory mechanism.
Biochemical and biophysical research communications Sep, 2022 | Pubmed ID: 35760008
BTB domains: A structural view of evolution, multimerization, and protein-protein interactions.
BioEssays : news and reviews in molecular, cellular and developmental biology Nov, 2022 | Pubmed ID: 36449605
Mechanisms of enhancer-promoter communication and chromosomal architecture in mammals and .
Frontiers in genetics , 2022 | Pubmed ID: 36531247
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