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Department of Biochemistry and Molecular Biology
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A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells.
BMC cell biology Oct, 2003 | Pubmed ID: 14583098
Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1.
BMC molecular biology Apr, 2004 | Pubmed ID: 15070431
Combinatorial identification of a novel consensus sequence for the covalent DNA-binding polyamide tallimustine.
Biochemistry Feb, 2005 | Pubmed ID: 15709763
The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks.
BMC molecular biology , 2005 | Pubmed ID: 16156902
REPSA: general combinatorial approach for identifying preferred ligand-DNA binding sequences.
Methods (San Diego, Calif.) Jun, 2007 | Pubmed ID: 17472894
Tousled homolog, TLK1, binds and phosphorylates Rad9; TLK1 acts as a molecular chaperone in DNA repair.
DNA repair Jan, 2009 | Pubmed ID: 18940270
The expression of Tousled kinases in CaP cell lines and its relation to radiation response and DSB repair.
The Prostate Sep, 2011 | Pubmed ID: 21647934
Analysis of eIF4E and 4EBP1 mRNAs in head and neck cancer.
The Laryngoscope Oct, 2011 | Pubmed ID: 21898433
TAT-mediated delivery of Tousled protein to salivary glands protects against radiation-induced hypofunction.
International journal of radiation oncology, biology, physics Sep, 2012 | Pubmed ID: 22285666
Recombinant AAV9-TLK1B administration ameliorates fractionated radiation-induced xerostomia.
Human gene therapy Jun, 2013 | Pubmed ID: 23614651
Tousled kinase activator, gallic acid, promotes homologous recombinational repair and suppresses radiation cytotoxicity in salivary gland cells.
Free radical biology & medicine Apr, 2016 | Pubmed ID: 26855419
louisiana state university health sciences center
Renjith Parameswaran Nair1,
Changyu Zheng2,
Gulshan Sunavala-Dossabhoy1
1Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center,
2Molecular Physiology and Therapeutics Branch, National Institute of Dental and Craniofacial Research, NIH, DHHS
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