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Oncode Institute and Department of Cell Chemical Biology
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Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis.
The Journal of experimental medicine Jan, 2010 | Pubmed ID: 20065063
Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting.
The Journal of biological chemistry May, 2012 | Pubmed ID: 22493445
ENDOGLIN is dispensable for vasculogenesis, but required for vascular endothelial growth factor-induced angiogenesis.
PloS one , 2014 | Pubmed ID: 24489709
Role of soluble endoglin in BMP9 signaling.
Proceedings of the National Academy of Sciences of the United States of America 09, 2019 | Pubmed ID: 31431534
Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas.
Cancer cell 03, 2020 | Pubmed ID: 32142668
Leiden University Medical Center
Jing Zhang1,
Midory Thorikay1,
Gerard van der Zon1,
Maarten van Dinther1,
Peter ten Dijke1
1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center
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