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Department of Pharmacology
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Regulation of WNK1 by an autoinhibitory domain and autophosphorylation.
The Journal of biological chemistry Dec, 2002 | Pubmed ID: 12374799
WNK1 activates ERK5 by an MEKK2/3-dependent mechanism.
The Journal of biological chemistry Feb, 2004 | Pubmed ID: 14681216
WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension.
Cell research Jan, 2005 | Pubmed ID: 15686619
WNK1 activates SGK1 to regulate the epithelial sodium channel.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2005 | Pubmed ID: 16006511
WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism.
The Journal of biological chemistry Oct, 2005 | Pubmed ID: 16081417
Biological cross-talk between WNK1 and the transforming growth factor beta-Smad signaling pathway.
The Journal of biological chemistry Jun, 2007 | Pubmed ID: 17392271
SLC26A9 is a Cl(-) channel regulated by the WNK kinases.
The Journal of physiology Oct, 2007 | Pubmed ID: 17673510
The roles of MAPKs in disease.
Cell research Apr, 2008 | Pubmed ID: 18347614
Regulation of a third conserved phosphorylation site in SGK1.
The Journal of biological chemistry Feb, 2009 | Pubmed ID: 19068477
Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.
The Journal of biological chemistry Aug, 2010 | Pubmed ID: 20525693
Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity.
The Journal of biological chemistry Nov, 2012 | Pubmed ID: 22989884
Protein kinase WNK3 regulates the neuronal splicing factor Fox-1.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2012 | Pubmed ID: 23027929
Regulation of OSR1 and the sodium, potassium, two chloride cotransporter by convergent signals.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2013 | Pubmed ID: 24191005
Phosphorylation or Mutation of the ERK2 Activation Loop Alters Oligonucleotide Binding.
Biochemistry Mar, 2016 | Pubmed ID: 26950759
Multistep regulation of autophagy by WNK1.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2016 | Pubmed ID: 27911840
WNK1 is an unexpected autophagy inhibitor.
Autophagy Feb, 2017 | Pubmed ID: 28282258
University of Texas Southwestern Medical Center
Aroon S. Karra1,
Steve Stippec1,
Melanie H. Cobb1
1Department of Pharmacology, University of Texas Southwestern Medical Center
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