Department of Biochemistry,
Department of Chemistry
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Parallel Reactions for Enantiomeric Quantification of Peptides by Mass Spectrometry This work was supported by the U.S. Department of Energy, Office of Energy Research. W.A.T. acknowledges fellowship support from Triangle Pharmaceuticals.
Angewandte Chemie (International ed. in English) Feb, 2001 | Pubmed ID: 11241614
Synthesis of B- and P-Heterocycles by Reaction of Cyclic Acetals and Ketals with Borinium and Phosphonium Ions.
The Journal of organic chemistry Apr, 1999 | Pubmed ID: 11674423
Quotient ratio method for quantitative enantiomeric determination by mass spectrometry.
Analytical chemistry Aug, 2002 | Pubmed ID: 12175167
Ligand and metal-ion effects in metal-ion clusters used for chiral analysis of alpha-hydroxy acids by the kinetic method.
Analytical and bioanalytical chemistry Aug, 2002 | Pubmed ID: 12185574
Chiral analysis by MS.
Analytical chemistry Jan, 2003 | Pubmed ID: 12530808
Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.
Nature methods Aug, 2005 | Pubmed ID: 16094384
Polar acetalization and transacetalization in the gas phase: the Eberlin reaction.
Chemical reviews Jan, 2006 | Pubmed ID: 16402776
A novel quantitative proteomics strategy to study phosphorylation-dependent peptide-protein interactions.
Journal of proteome research Jan, 2007 | Pubmed ID: 17203957
PTEN-deficient intestinal stem cells initiate intestinal polyposis.
Nature genetics Feb, 2007 | Pubmed ID: 17237784
Rapid ambient mass spectrometric profiling of intact, untreated bacteria using desorption electrospray ionization.
Chemical communications (Cambridge, England) Jan, 2007 | Pubmed ID: 17279261
A novel quantitative proteomics reagent based on soluble nanopolymers.
Chemical communications (Cambridge, England) Mar, 2007 | Pubmed ID: 17356773
Soluble nanopolymer-based phosphoproteomics for studying protein phosphatase.
Methods (San Diego, Calif.) Jul, 2007 | Pubmed ID: 17532516
Profiling constitutive proteolytic events in vivo.
The Biochemical journal Oct, 2007 | Pubmed ID: 17650073
Soluble polymer-based isotopic labeling (SoPIL): a new strategy to discover protein biomarkers?
Expert review of proteomics Oct, 2007 | Pubmed ID: 17941815
Quantitative analysis of snake venoms using soluble polymer-based isotope labeling.
Molecular & cellular proteomics : MCP Apr, 2008 | Pubmed ID: 18089550
Playing tag with quantitative proteomics.
Analytical and bioanalytical chemistry Jan, 2009 | Pubmed ID: 18843486
Quantitative phospho-proteomics based on soluble nanopolymers.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19241010
Identification of serine/threonine kinase substrates in the human pathogen group B streptococcus.
Journal of proteome research May, 2009 | Pubmed ID: 19309132
In-depth analyses of kinase-dependent tyrosine phosphoproteomes based on metal ion-functionalized soluble nanopolymers.
Molecular & cellular proteomics : MCP Oct, 2010 | Pubmed ID: 20562096
Cloning, expression, and hemostatic activities of a disintegrin, r-mojastin 1, from the mohave rattlesnake (Crotalus scutulatus scutulatus).
Thrombosis research Sep, 2010 | Pubmed ID: 20598348
Regulation of Syk by phosphorylation on serine in the linker insert.
The Journal of biological chemistry Dec, 2010 | Pubmed ID: 20956537
Purification and characterization of a metalloproteinase, Porthidin-1, from the venom of Lansberg's hog-nosed pitvipers (Porthidium lansbergii hutmanni).
Toxicon : official journal of the International Society on Toxinology Mar, 2011 | Pubmed ID: 21255600
Phosphorylation assay based on multifunctionalized soluble nanopolymer.
Analytical chemistry Apr, 2011 | Pubmed ID: 21395237
Identification of drug targets in vitro and in living cells by soluble-nanopolymer-based proteomics.
Angewandte Chemie (International ed. in English) Apr, 2011 | Pubmed ID: 21455918
Proteomic studies of Syk-interacting proteins using a novel amine-specific isotope tag and GFP nanotrap.
Journal of the American Society for Mass Spectrometry Feb, 2011 | Pubmed ID: 21472591
Aptamer in bioanalytical applications.
Analytical chemistry Jun, 2011 | Pubmed ID: 21524128
Facile determination of double bond position in unsaturated fatty acids and esters by low temperature plasma ionization mass spectrometry.
Analytical chemistry Jun, 2011 | Pubmed ID: 21539336
Direct detection of fatty acid ethyl esters using low temperature plasma (LTP) ambient ionization mass spectrometry for rapid bacterial differentiation.
The Analyst Aug, 2011 | Pubmed ID: 21706093
Functionalized soluble nanopolymers for phosphoproteome analysis.
Methods in molecular biology (Clifton, N.J.) , 2011 | Pubmed ID: 21948422
Regulation of parkin and PINK1 by neddylation.
Human molecular genetics Jun, 2012 | Pubmed ID: 22388932
Sensitive kinase assay linked with phosphoproteomics for identifying direct kinase substrates.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2012 | Pubmed ID: 22451900
Chemical visualization of phosphoproteomes on membrane.
Molecular & cellular proteomics : MCP Sep, 2012 | Pubmed ID: 22593177
Identification of cytoskeletal elements enclosing the ATP pools that fuel human red blood cell membrane cation pumps.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2012 | Pubmed ID: 22745158
Multiplexed quantitation of protein expression and phosphorylation based on functionalized soluble nanopolymers.
Journal of the American Chemical Society Nov, 2012 | Pubmed ID: 23088311
Identification of the components of a glycolytic enzyme metabolon on the human red blood cell membrane.
The Journal of biological chemistry Jan, 2013 | Pubmed ID: 23150667
Is phosphoproteomics ready for clinical research?
Clinica chimica acta; international journal of clinical chemistry May, 2013 | Pubmed ID: 23159844
2012 ASMS Fall Workshop: mass spectrometry-based phosphorylation analysis and phosphoproteomics.
Journal of the American Society for Mass Spectrometry Mar, 2013 | Pubmed ID: 23381688
Syk inhibits the activity of protein kinase A by phosphorylating tyrosine 330 of the catalytic subunit.
The Journal of biological chemistry Apr, 2013 | Pubmed ID: 23447535
A quantitative proteomics-based competition binding assay to characterize pITAM-protein interactions.
Analytical chemistry May, 2013 | Pubmed ID: 23611696
Quantitative measurement of phosphoproteome response to osmotic stress in arabidopsis based on Library-Assisted eXtracted Ion Chromatogram (LAXIC).
Molecular & cellular proteomics : MCP Aug, 2013 | Pubmed ID: 23660473
Quantitative phosphoproteomics identifies SnRK2 protein kinase substrates and reveals the effectors of abscisic acid action.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2013 | Pubmed ID: 23776212
Identification of direct tyrosine kinase substrates based on protein kinase assay-linked phosphoproteomics.
Molecular & cellular proteomics : MCP Oct, 2013 | Pubmed ID: 23793017
Intracellular targets for a phosphotyrosine peptidomimetic include the mitotic kinesin, MCAK.
Biochemical pharmacology Sep, 2013 | Pubmed ID: 23830822
Phosphatase of regenerating liver 3 (PRL3) provokes a tyrosine phosphoproteome to drive prometastatic signal transduction.
Molecular & cellular proteomics : MCP Dec, 2013 | Pubmed ID: 24030100
Tissue phosphoproteomics with PolyMAC identifies potential therapeutic targets in a transgenic mouse model of HER2 positive breast cancer.
Electrophoresis Dec, 2014 | Pubmed ID: 24723360
Quantitation of the phosphoproteome using the library-assisted extracted ion chromatogram (LAXIC) strategy.
Methods in molecular biology (Clifton, N.J.) , 2014 | Pubmed ID: 24792004
Global phosphoproteomics of activated B cells using complementary metal ion functionalized soluble nanopolymers.
Analytical chemistry Jul, 2014 | Pubmed ID: 24905233
Specific visualization and identification of phosphoproteome in gels.
Analytical chemistry Jul, 2014 | Pubmed ID: 24941108
Identification of ERK1 Direct Substrates using Stable Isotope Labeled Kinase Assay-Linked Phosphoproteomics.
Molecular & cellular proteomics : MCP Jul, 2014 | Pubmed ID: 25022875
Current technologies to identify protein kinase substrates in high throughput.
Frontiers in biology Apr, 2013 | Pubmed ID: 25110472
Nitric oxide negatively regulates abscisic acid signaling in guard cells by S-nitrosylation of OST1.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2015 | Pubmed ID: 25550508
The sensor histidine kinase RgfC affects group B streptococcal virulence factor expression independent of its response regulator RgfA.
Infection and immunity Mar, 2015 | Pubmed ID: 25561709
The methyl-CpG-binding protein MBD7 facilitates active DNA demethylation to limit DNA hyper-methylation and transcriptional gene silencing.
Molecular cell Mar, 2015 | Pubmed ID: 25684209
Universal non-antibody detection of protein phosphorylation using pIMAGO.
Current protocols in chemical biology Mar, 2015 | Pubmed ID: 25727060
Sensitive measurement of total protein phosphorylation level in complex protein samples.
The Analyst May, 2015 | Pubmed ID: 25857711
In-Depth Analyses of B Cell Signaling Through Tandem Mass Spectrometry of Phosphopeptides Enriched by PolyMAC.
International journal of mass spectrometry Feb, 2015 | Pubmed ID: 25954137
Time-Resolved Proteomic Visualization of Dendrimer Cellular Entry and Trafficking.
Journal of the American Chemical Society Oct, 2015 | Pubmed ID: 26425924
MET18 Connects the Cytosolic Iron-Sulfur Cluster Assembly Pathway to Active DNA Demethylation in Arabidopsis.
PLoS genetics Oct, 2015 | Pubmed ID: 26492035
Identification of Direct Kinase Substrates via Kinase Assay-Linked Phosphoproteomics.
Methods in molecular biology (Clifton, N.J.) , 2016 | Pubmed ID: 26584932
The E3 ubiquitin ligase CHIP mediates ubiquitination and proteasomal degradation of PRMT5.
Biochimica et biophysica acta Feb, 2016 | Pubmed ID: 26658161
Multiplexed Imaging of Protein Phosphorylation on Membranes Based on Ti(IV) Functionalized Nanopolymers.
Chembiochem : a European journal of chemical biology 05, 2016 | Pubmed ID: 27037847
BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy.
The Journal of biological chemistry Oct, 2016 | Pubmed ID: 27528605
Three-Dimensionally Functionalized Reverse Phase Glycoprotein Array for Cancer Biomarker Discovery and Validation.
Journal of the American Chemical Society 11, 2016 | Pubmed ID: 27933927
A pair of transposon-derived proteins function in a histone acetyltransferase complex for active DNA demethylation.
Cell research Feb, 2017 | Pubmed ID: 27934869
Kinase Assay-Linked Phosphoproteomics: Discovery of Direct Kinase Substrates.
Methods in enzymology , 2017 | Pubmed ID: 28137576
MST50 is involved in multiple MAP kinase signaling pathways in Magnaporthe oryzae.
Environmental microbiology 05, 2017 | Pubmed ID: 28244240
Phosphoproteins in extracellular vesicles as candidate markers for breast cancer.
Proceedings of the National Academy of Sciences of the United States of America 03, 2017 | Pubmed ID: 28270605
Estimating the Efficiency of Phosphopeptide Identification by Tandem Mass Spectrometry.
Journal of the American Society for Mass Spectrometry 06, 2017 | Pubmed ID: 28283928
The SnRK2 kinases modulate miRNA accumulation in Arabidopsis.
PLoS genetics 04, 2017 | Pubmed ID: 28419088
Identification of Plant Kinase Substrates Based on Kinase Assay-Linked Phosphoproteomics.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 28730489
A protein complex regulates RNA processing of intronic heterochromatin-containing genes in .
Proceedings of the National Academy of Sciences of the United States of America 08, 2017 | Pubmed ID: 28808009
EZH2 Modifies Sunitinib Resistance in Renal Cell Carcinoma by Kinome Reprogramming.
Cancer research 12, 2017 | Pubmed ID: 28978636
MAP Kinase Cascades Regulate the Cold Response by Modulating ICE1 Protein Stability.
Developmental cell 12, 2017 | Pubmed ID: 29056551
Recent advances in phosphoproteomics and application to neurological diseases.
The Analyst Nov, 2017 | Pubmed ID: 29094114
Identification of Upstream Kinases by Fluorescence Complementation Mass Spectrometry.
ACS central science Oct, 2017 | Pubmed ID: 29104924
Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases.
The Plant cell 01, 2018 | Pubmed ID: 29233856
Acquisition of Cholangiocarcinoma Traits during Advanced Hepatocellular Carcinoma Development in Mice.
The American journal of pathology 03, 2018 | Pubmed ID: 29248454
Reciprocal Regulation of the TOR Kinase and ABA Receptor Balances Plant Growth and Stress Response.
Molecular cell 01, 2018 | Pubmed ID: 29290610
Analytical Pipeline for Discovery and Verification of Glycoproteins from Plasma-Derived Extracellular Vesicles as Breast Cancer Biomarkers.
Analytical chemistry 05, 2018 | Pubmed ID: 29629753
Replacement of C-O by P-O in Cyclic Acetals and Ketals.
Angewandte Chemie (International ed. in English) Feb, 1999 | Pubmed ID: 29711658
Arabidopsis Duodecuple Mutant of PYL ABA Receptors Reveals PYL Repression of ABA-Independent SnRK2 Activity.
Cell reports 06, 2018 | Pubmed ID: 29898403
Universal Plant Phosphoproteomics Workflow and Its Application to Tomato Signaling in Response to Cold Stress.
Molecular & cellular proteomics : MCP 10, 2018 | Pubmed ID: 30006488
Highly Efficient Phosphoproteome Capture and Analysis from Urinary Extracellular Vesicles.
Journal of proteome research 09, 2018 | Pubmed ID: 30080416
High-Throughput Phosphorylation Screening and Validation through Ti(IV)-Nanopolymer Functionalized Reverse Phase Phosphoprotein Array.
Analytical chemistry 09, 2018 | Pubmed ID: 30103608
Arabidopsis AGDP1 links H3K9me2 to DNA methylation in heterochromatin.
Nature communications 10, 2018 | Pubmed ID: 30382101
Leucine-rich repeat extensin proteins regulate plant salt tolerance in .
Proceedings of the National Academy of Sciences of the United States of America 12, 2018 | Pubmed ID: 30514814
Arabinose biosynthesis is critical for salt stress tolerance in Arabidopsis.
The New phytologist 10, 2019 | Pubmed ID: 31009077
Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 08, 2019 | Pubmed ID: 31162944
Methyltransferase-like 21c methylates and stabilizes the heat shock protein Hspa8 in type I myofibers in mice.
The Journal of biological chemistry 09, 2019 | Pubmed ID: 31346037
Tracking Pathogen Infections by Time-Resolved Chemical Proteomics.
Angewandte Chemie (International ed. in English) 02, 2020 | Pubmed ID: 31769915
Sequential phosphoproteomics and N-glycoproteomics of plasma-derived extracellular vesicles.
Nature protocols 01, 2020 | Pubmed ID: 31863077
Mapping proteome-wide targets of protein kinases in plant stress responses.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2020 | Pubmed ID: 31992638
A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants.
Nature communications 01, 2020 | Pubmed ID: 32001690
A phosphorylation-based switch controls TAA1-mediated auxin biosynthesis in plants.
Nature communications 02, 2020 | Pubmed ID: 32015349
Plasma-Derived Extracellular Vesicle Phosphoproteomics through Chemical Affinity Purification.
Journal of proteome research May, 2020 | Pubmed ID: 32396726
1Department of Plant Biology, Carnegie Institute for Science,
2Graduate School of Pharmaceutical Sciences, Kyoto University,
3Department of Biochemistry, Purdue University,
4Department of Chemistry, Purdue University,
5Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences
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