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National Key Laboratory of Collateral Disease Research and Innovative Chinese Medicine

1 ARTICLES PUBLISHED IN JoVE

Medicine

Estrogen-Like Effect of Bazi Bushen Capsule in Ovariectomized Rats

Dandong Wang^1,2,3, Liping Chang^1,2,3, Jiameng Hao^1,2,3, Jiehan Zhang^1,2,3, Yahui Song^2,3,4, Kun Ma^2,3,4, Shaolan Zhang^2,3,4, Cuiru Li^2,3,4, Jiaojiao Gu^2,3,4, Yunlong Hou^1,2,3, Yiling Wu^1,2,3

¹Hebei Medical University, ²National Key Laboratory of Collateral Disease Research and Innovative Chinese Medicine, ³Key Laboratory of Cardio-Cerebral Vessel Collateral Disease, State Administration of Traditional Chinese Medicine, ⁴Hebei University of Traditional Chinese Medicine

Presented here is a protocol to show that Bazi Bushen capsule (BZBS) can regulate the RANKL/OPG signaling pathway in the ovariectomized rodent model through its estrogen-like effect.