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Shantou University and the Chinese University of Hong Kong

2 ARTICLES PUBLISHED IN JoVE

JoVE Journal

Use of In Vivo Single-fiber Recording and Intact Dorsal Root Ganglion with Attached Sciatic Nerve to Examine the Mechanism of Conduction Failure

Honghui Mao^*1,2, Xiuchao Wang^*1,3, Wen Chen⁴, FengYu Liu⁵, You Wan⁵, Sanjue Hu¹, Junling Xing^1,6

¹Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, ²Department of Toxicology, School of Public Health, ShanXi Medical University, ³Department of Psychology, Fourth Military Medical University, ⁴Department of Neurobiology, School of Basic Medical Sciences, Advanced Innovation Center for Human Brain Protection, Capital Medical University, ⁵Neuroscience Research Institute, Key Lab for Neuroscience, Ministry of Education/National Health Commission, Peking University, ⁶Department of Radiation Biology, Faculty of Preventive Medicine, Fourth Military Medical University

Single-fiber recording is an effective electrophysiological technique that is applicable to the central and peripheral nervous systems. Along with the preparation of intact DRG with the attached sciatic nerve, the mechanism of conduction failure is examined. Both protocols improve the understanding of the peripheral nervous system's relationship with pain.

Medicine

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Xiaoting Mai^*1, Shaofen Huang^*1, Wen Chen¹, Tsz Kin Ng^1,2,3, Haoyu Chen¹

¹Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, ²Shantou University Medical College, ³Department of Ophthalmology and Visual Sciences, the Chinese University of Hong Kong

Here, we describe an in vivo imaging technique using optical coherence tomography to facilitate the diagnosis and quantitative measurement of retinopathy in mice.