Ernest Gallo Clinic and Research Center, University of California, San Francisco

1 ARTICLES PUBLISHED IN JoVE

Medicine

Mouse Model of Middle Cerebral Artery Occlusion

Terrance Chiang¹, Robert O. Messing¹, Wen-Hai Chou^1,2

¹Department of Neurology, Ernest Gallo Clinic and Research Center, University of California, San Francisco, ²Department of Biological Sciences, Kent State University

We demonstrate in the video a method for producing a middle cerebral artery occlusion in adult mice using an intraluminal monofilament. We also show how to evaluate the extent of cerebral infarction by 2,3,5-triphenyltetrazolium chloride (TTC) staining.