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Mouse Model of Middle Cerebral Artery Occlusion

DOI :

10.3791/2761-v

9:43 min

February 13th, 2011

February 13th, 2011

75,457 Views

1Department of Neurology, Ernest Gallo Clinic and Research Center, University of California, San Francisco, 2Department of Biological Sciences, Kent State University

We demonstrate in the video a method for producing a middle cerebral artery occlusion in adult mice using an intraluminal monofilament. We also show how to evaluate the extent of cerebral infarction by 2,3,5-triphenyltetrazolium chloride (TTC) staining.

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Mouse Model

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