MSC Expansion and Preparation of Activated MSC Spheroids in 3-D Hanging Drop Cultures
4:50
Intraperitoneal Delivery of Intact Spheroids
8:02
Results: Spheroids Produced Using MSC Hanging Drop Cultures
9:31
Conclusion
TRANSCRIÇÃO
The overall goal of these experiments is to efficiently generate and inject therapeutic spherical aggregates, or spheroids, of mesenchymal stem/stromal cells, or MSCs, primed under xeno-free conditions in experimental and clinical applications. Th
Sign in or start your free trial to access this content
The therapeutic potential of mesenchymal stem/stromal cells (MSCs) is well-documented, however the best method of preparing the cells for patients remains controversial. Herein, we communicate protocols to efficiently generate and administer therapeutic spherical aggregates or 'spheroids' of MSCs primed under xeno-free conditions for experimental and clinical applications.