Methods Collections

<p>The study of protein-protein interactions is key to understanding the network of molecular interactions underlying biological effects, and defining how individual proteins perform their functional role within a cell.&nbsp;A detailed...

<p>Chloroplasts are the organelles that define plants. Along with many other metabolic, developmental and signalling functions, chloroplasts are responsible for photosynthesis, the process where&nbsp;sunlight energy is harnessed to pow...

<p>Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by the progressive death of motor neurons and muscle denervation. This leads to respiratory failure within 3 to 5 years and current treatme...

<p>Advancements in ultrasound transducer and computer technology have permitted for the visualization of cardiac structures with excellent spatial and temporal resolution in three dimensions. 3D echocardiography provided new insights i...

<p>Rabies is an acute progressive encephalitis caused by a lyssavirus. The case fatality of this zoonosis is the highest for any infectious disease. Although laboratory techniques on rabies have progressed greatly over the last century...

<p>Entomology has a long history of rigorous and accessible investigation into the basis of insect behavior, morphology, and physiology. Today, entomologists use a variety of methods to study&nbsp;insects, drawing from diverse fields. ...

<p>Mosquitoes are the world’s deadliest animals. They spread a wide range of parasitic and viral diseases, including malaria and dengue, thereby causing millions of human deaths every year.. Insecticide resistance among mosquito popula...

<p>Prolonged lifespan and delayed childbearing have prompted the research of reliable methods to preserve fertility for later in life. Such interventions that heavily rely on the cryopreservation of mature gametes (eggs or sperm) and e...

<p>Obesity has become a major worldwide public health issue, dramatically increasing the risk of developing cardiovascular disease, type 2 diabetes, and liver diseases. Obesity is characterized by an increase in adipose tissue (AT) mas...

<p>Cancer research has focused on the cancer cell, its proliferation rates, apoptosis resistance, mutation rates, sensitivity to radio and chemotherapy. However, tumor metastatic progression involves many other cellular and molecular p...

<p>Vector-borne diseases are re-emerging global health threats that account for nearly one-quarter of all infectious diseases. They particularly impact sub-tropical and tropical regions of the world where underserved populations are di...

<p>Parkinson’s disease is a common neurodegenerative disorder resulting in progressive motor and cognitive decline, among other symptoms. While we have recently celebrated the 200^th anniversary of the discovery of Parkinson’...

<p>Anxiety affects 1 in 3 adults, and is highly comorbid with many other disorders, including psychiatric and neurodegenerative disorders. Stress is a major player in the development of anxiety and represents a risk factor for many psy...

<p>Integrative structural biology uses a large variety of biophysical methods that provide detailed knowledge of the atomic and molecular structure of macromolecules, isolated or in their native environment. This provides a better unde...