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Chapter 21

The Endocrine System

An Overview of the Endocrine System
An Overview of the Endocrine System
The endocrine system is made of glands and organs that produce and secrete hormones. Hormones are chemical signals that act as messengers between ...
Structures of the Endocrine System
Structures of the Endocrine System
The endocrine system is composed of glands, tissues, and organs distributed throughout the body. Endocrine glands are ductless glands that secrete ...
Chemical Signaling in the Endocrine System
Chemical Signaling in the Endocrine System
A signaling cascade is a sequence of events that transfers information within or between cells, resulting in a response in the target cell. Hormones are ...
Types of Hormones
Types of Hormones
Hormones can be classified into steroids, eicosanoids, amino acid-based derivatives, and peptide hormones based on their structures. Steroids and ...
Secondary Messengers in Hormone Action
Secondary Messengers in Hormone Action
Water-soluble hormones cannot move across the plasma membrane, so they use protein receptors that span the membrane to trigger intracellular signaling ...
Target Cell Response to Hormones
Target Cell Response to Hormones
Hormones bind to receptors on a target cell’s surface or interior and initiate various cellular ...
Regulation of Hormone Secretion
Regulation of Hormone Secretion
Hormone secretion is regulated by different types of signals, including neural, humoral, and hormonal stimuli. Neural stimuli are triggered by the ...
The Pituitary Gland
The Pituitary Gland
The pituitary gland is a small endocrine organ located in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct ...
Hormones of the Pituitary Gland
Hormones of the Pituitary Gland
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to ...
The Thyroid Gland
The Thyroid Gland
The thyroid gland is a small, butterfly-shaped gland. It covers the anterior surface of the trachea in the neck region. It has two lateral lobes connected ...
Synthesis and Regulation of Thyroid Hormones
Synthesis and Regulation of Thyroid Hormones
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the ...
Functions of Thyroid Hormones
Functions of Thyroid Hormones
The thyroid hormone, or TH, is essential for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and ...
Synthesis and Functions of Calcitonin
Synthesis and Functions of Calcitonin
Calcitonin is a polypeptide hormone that regulates calcium levels in body fluids. The parafollicular cells or C cells are present in the follicular ...
The Parathyroid Glands
The Parathyroid Glands
The thyroid gland's posterior surface contains two embedded pairs of parathyroid glands. They are separated from the thyroid gland by a dense ...
Anatomy of the Adrenal Glands
Anatomy of the Adrenal Glands
The adrenal or supra-renal glands are paired, pyramid-shaped glands located above the kidney and in line with the twelfth rib.  When the body ...
Hormones of the Adrenal Glands
Hormones of the Adrenal Glands
The adrenal hormones are crucial for the body's electrolyte balance and stress response. The adrenal cortex produces over two dozen types of ...
Adrenal Gland Disorders
Adrenal Gland Disorders
Adrenal gland disorders occur when the concentration of adrenal hormones produced is too high or too low. Adrenal insufficiency occurs when the adrenal ...
The Pineal Gland
The Pineal Gland
The pineal gland is a small endocrine gland named for its pinecone shape. This gland is located on the roof of the third ventricle within the ...
Gonadal and Placental Hormones
Gonadal and Placental Hormones
The gonads, the testes in males, and the ovaries in females produce gonadal hormones. Testosterone is the primary male gonadal androgen. It is responsible ...
Cells and Secretions of the Pancreas
Cells and Secretions of the Pancreas
The pancreas is a glandular organ in the abdominal cavity that is part of the digestive and endocrine systems. It consists of exocrine and endocrine cells ...
Hormones Regulating Blood Glucose
Hormones Regulating Blood Glucose
The pancreatic hormones glucagon and insulin regulate blood glucose levels. Between meals or during fasting, the blood glucose levels drop, triggering the ...
Diabetes Mellitus: Overview and Type I Subtype
Diabetes Mellitus: Overview and Type I Subtype
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or ...
Diabetes Mellitus: Type 2 and Gestational
Diabetes Mellitus: Type 2 and Gestational
In Type 2 or insulin-independent diabetes, the insulin receptors on the cells stop responding to insulin, developing resistance to insulin functions. This ...
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