JoVE Encyclopedia of Experiments
Encyclopedia of Experiments
This video demonstrates the staining of the damaged cornea using fluorescein dye to evaluate the extent of autoimmune dry eye disease in a rat model. The green fluorescence spots of the stained collagen fibers indicate corneal epithelial damaged cells.
All procedures involving animal models have been reviewed by the local institutional animal care committee and the JoVE veterinary review board.
1. Assessment of Dry Eye Features
Measure corneal damage with fluorescein staining.
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Source: Hou Ahiua, et al. A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue. J.Vis. Exp. (2017)
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