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Neuroscience

Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke

Published: September 1st, 2023

DOI:

10.3791/65405

1Guangzhou Medical University, 2Department of Rehabilitation Medicine, The Seventh Affiliated Hospital of Sun Yat-sen University, 3Department of Rehabilitation Medicine, The Fifth Affiliated Hospital of Guangzhou Medical University, 4Clinical Medical College of Acupuncture and Rehabilitation, Guangzhou University of Traditional Chinese Medicine, 5School of Traditional Chinese Medicine, Jinan University, 6Department of Stomatology, Second Clinical Medical College, Dongguan Campus of Guangdong Medical University
* These authors contributed equally

ERRATUM NOTICE

Important: There has been an erratum issued for this article. Read more …

The purpose of this study is to provide an important reference for the standard clinical operation of motor imagery brain-computer interface (MI-BCI) for upper limb motor dysfunction after stroke.

The rehabilitation effect of patients with moderate or severe upper limb motor dysfunction after stroke is poor, which has been the focus of research owing to the difficulties encountered. Brain-computer interface (BCI) represents a hot frontier technology in brain neuroscience research. It refers to the direct conversion of the sensory perception, imagery, cognition, and thinking of users or subjects into actions, without reliance on peripheral nerves or muscles, to establish direct communication and control channels between the brain and external devices. Motor imagery brain-computer interface (MI-BCI) is the most common clinical application of rehabilitation as a non-invasive means of rehabilitation. Previous clinical studies have confirmed that MI-BCI positively improves motor dysfunction in patients after stroke. However, there is a lack of clinical operation demonstration. To that end, this study describes in detail the treatment of MI-BCI for patients with moderate and severe upper limb dysfunction after stroke and shows the intervention effect of MI-BCI through clinical function evaluation and brain function evaluation results, thereby providing ideas and references for clinical rehabilitation application and mechanism research.

Nearly 85% of stroke patients have motor dysfunction1, especially due to the limited rehabilitation effect of patients with moderate and severe upper limb motor dysfunction, which seriously affects patients' ability to live independent daily lives and has been the focus and difficulty of research. Non-invasive brain-computer interface (BCI) is known as an emerging treatment for rehabilitation of motor dysfunction after stroke2. BCI is the direct conversion of the sensory perception, imagery, cognition, and thinking of users or subjects into actions, without reliance on peripheral nerves or muscles, to establish direct co....

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This project was approved by the Medical Ethics Association of the Fifth Affiliated Hospital of Guangzhou Medical University (approval No. KY01-2021-05-01) on August 19, 2021. The trial was registered in the Chinese Clinical Trials Registry (registration number: NO. ChiCTR2100050162) on August 19, 2021. All patients signed the informed consent form.

1. Recruitment

  1. Inclusion criteria
    1. Recruit patients who meet the diagnostic criteria of stroke formulated .......

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The study presents the clinical function and remodeling of brain function before and after MI-BCI intervention in a 36-year-old male stroke patient. More than 4 months after cerebral hemorrhage, the imaging results showed chronic bleeding focus in the right frontal lobe and the right basal ganglia region-radiative crown region. The patient was diagnosed with left limb motor dysfunction during convalescence from a cerebral hemorrhage. Simple outpatient treatment of MI-BCI was performed in the hospital for 10 days (30 min/.......

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The rehabilitation period for moderate and severe upper limb motor dysfunction after stroke is long and the recovery is difficult, which has always been the focus of clinical rehabilitation research18. Traditional upper limb rehabilitation training is mostly simple peripheral intervention or central intervention19. Meanwhile, due to the lack of active participation of patients with moderate and severe limb dysfunction, passive treatment is mainly used, with poor rehabilitat.......

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This study was supported by the National Science Foundation of Guangdong Province (No.2023A1515010586), Guangzhou clinical characteristic technology construction project (2023C-TS19), Education Science Planning Project of Guangdong Province (No.2022GXJK299), the General Guidance Program of Guangzhou Municipal Health and Family Planning (20221A011109, 20231A011111), 2022 Guangzhou Higher Education Teaching Quality and Teaching Reform Project of Higher Education Teaching reform General project (No.2022JXGG088/02-408-2306040XM), 2022 Guangzhou Medical University Student Innovation Ability Improvement Plan project (No.PX-66221494/02-408-2304-19062XM), 2021 school-level ed....

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NameCompanyCatalog NumberComments
MI-BCIRui Han, ChinaRuiHan BangdeNA
E-Prime version 3.0behavioral research software.
fNIRSHui Chuang, ChinaNirSmart-500NA
NirSparkpreprocess near-infrared data

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Erratum

Erratum: Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke

An erratum was issued for: Motor Imagery Brain-Computer Interface in Rehabilitation of Upper Limb Motor Dysfunction After Stroke. The Authors section was updated from:

Yongchun Jiang1,2,3
Junxiao Yin4
Biyi Zhao1,3,5
Yajie Zhang1,3
Tingting Peng1,3
Wanqi Zhuang1,3
Siqing Wang1,3
Siqi Huang1,3
Meilian Zhong1,2,3
Yanni Zhang1,3
Guibing Tang1,3
Bingchi Shen6
Haining Ou1,3
Yuxin Zheng2,3 
Qiang Lin2,3
1Guangzhou Medical University
2Department of Rehabilitation Medicine, The Seventh Affiliated Hospital of Sun Yat-sen University
3Department of Rehabilitation Medicine, The Fifth Affiliated Hospital of Guangzhou Medical University
4Clinical Medical College of Acupuncture and Rehabilitation, Guangzhou University of Traditional Chinese Medicine
5School of Traditional Chinese Medicine, Jinan University
6Department of Stomatology, Second Clinical Medical College, Dongguan Campus of Guangdong Medical University
 

to:

Yongchun Jiang1,2,3
Junxiao Yin4
Biyi Zhao1,3,5
Yajie Zhang1,3
Tingting Peng1,3
Wanqi Zhuang1,3
Siqing Wang1,3
Siqi Huang1,3
Meilian Zhong1,3
Yanni Zhang1,3
Guibing Tang1,3
Bingchi Shen6
Haining Ou1,3
Yuxin Zheng2,3 
Qiang Lin2,3
1Guangzhou Medical University
2Department of Rehabilitation Medicine, The Seventh Affiliated Hospital of Sun Yat-sen University
3Department of Rehabilitation Medicine, The Fifth Affiliated Hospital of Guangzhou Medical University
4Clinical Medical College of Acupuncture and Rehabilitation, Guangzhou University of Traditional Chinese Medicine
5School of Traditional Chinese Medicine, Jinan University
6Department of Stomatology, Second Clinical Medical College, Dongguan Campus of Guangdong Medical University
 

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