Department of Nephrology
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PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry Oct, 2002 | Pubmed ID: 12167629
Activation of mitochondrial apoptotic pathways in human renal allografts after ischemiareperfusion injury.
Transplantation Jul, 2003 | Pubmed ID: 12865785
Anti-interleukin-2 receptor antibodies for the prevention of rejection in pediatric renal transplant patients: current status.
Paediatric drugs , 2003 | Pubmed ID: 14510627
Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator.
The Journal of biological chemistry Sep, 2004 | Pubmed ID: 15247260
The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells.
The Journal of biological chemistry Nov, 2005 | Pubmed ID: 16131493
Pseudomonas aeruginosa inhibits endocytic recycling of CFTR in polarized human airway epithelial cells.
American journal of physiology. Cell physiology Mar, 2006 | Pubmed ID: 16236828
Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells.
The Journal of biological chemistry Aug, 2007 | Pubmed ID: 17462998
The Pseudomonas aeruginosa secreted protein PA2934 decreases apical membrane expression of the cystic fibrosis transmembrane conductance regulator.
Infection and immunity Aug, 2007 | Pubmed ID: 17502391
Mizoribine corrects defective nephrin biogenesis by restoring intracellular energy balance.
Journal of the American Society of Nephrology : JASN Sep, 2007 | Pubmed ID: 17687078
The DeltaF508-CFTR mutation results in increased biofilm formation by Pseudomonas aeruginosa by increasing iron availability.
American journal of physiology. Lung cellular and molecular physiology Jul, 2008 | Pubmed ID: 18359885
c-Cbl facilitates endocytosis and lysosomal degradation of cystic fibrosis transmembrane conductance regulator in human airway epithelial cells.
The Journal of biological chemistry Aug, 2010 | Pubmed ID: 20525683
DAB2 facilitates AP-2 independent recruitment of CFTR to endocytic vesicles in polarized human airway epithelial cells.
The Journal of biological chemistry Mar, 2012 | Pubmed ID: 22399289
Membrane trafficking in podocyte health and disease.
Pediatric nephrology (Berlin, Germany) Sep, 2013 | Pubmed ID: 22932996
Tissue-specific control of CFTR endocytosis by Dab2: Cargo recruitment as a therapeutic target.
Communicative & integrative biology Sep, 2012 | Pubmed ID: 23181163
Tgf-β1 inhibits Cftr biogenesis and prevents functional rescue of ΔF508-Cftr in primary differentiated human bronchial epithelial cells.
PloS one , 2013 | Pubmed ID: 23671668
c-Cbl reduces stability of rescued ∆F508-CFTR in human airway epithelial cells: Implications for cystic fibrosis treatment.
Communicative & integrative biology Mar, 2013 | Pubmed ID: 23750297
LMTK2-mediated phosphorylation regulates CFTR endocytosis in human airway epithelial cells.
The Journal of biological chemistry May, 2014 | Pubmed ID: 24727471
Atypical Hemolytic Uremic Syndrome and Chronic Ulcerative Colitis Treated with Eculizumab.
International journal of medical and pharmaceutical case reports , 2015 | Pubmed ID: 27135055
Tubulointerstitial nephritis: diagnosis, treatment, and monitoring.
Pediatric nephrology (Berlin, Germany) 04, 2017 | Pubmed ID: 27155873
Endocytic Trafficking at the Mature Podocyte Slit Diaphragm.
Frontiers in pediatrics , 2017 | Pubmed ID: 28286744
Editorial: Nephrotic Syndrome in Pediatric Patients.
Frontiers in pediatrics , 2017 | Pubmed ID: 28824891
Extra-renal manifestations of atypical hemolytic uremic syndrome.
Pediatric nephrology (Berlin, Germany) 08, 2019 | Pubmed ID: 30109445
Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study.
Kidney international reports Nov, 2018 | Pubmed ID: 30450464
The human nephrin YRSL motif is essential for podocyte foot process organization and slit diaphragm formation during glomerular development.
The Journal of biological chemistry 07, 2019 | Pubmed ID: 31152064
Identification of a novel functional miR-143-5p recognition element in the Cystic Fibrosis Transmembrane Conductance Regulator 3'UTR.
AIMS genetics , 2018 | Pubmed ID: 31435512
Transforming Growth Factor-β1 Selectively Recruits microRNAs to the RNA-Induced Silencing Complex and Degrades CFTR mRNA under Permissive Conditions in Human Bronchial Epithelial Cells.
International journal of molecular sciences Oct, 2019 | Pubmed ID: 31590401
Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells.
Molecular therapy : the journal of the American Society of Gene Therapy 04, 2020 | Pubmed ID: 32059764
TGF-β1 Augments the Apical Membrane Abundance of Lemur Tyrosine Kinase 2 to Inhibit CFTR-Mediated Chloride Transport in Human Bronchial Epithelia.
Frontiers in cell and developmental biology , 2020 | Pubmed ID: 32117984
The Role of MicroRNA in the Airway Surface Liquid Homeostasis.
International journal of molecular sciences May, 2020 | Pubmed ID: 32481719
1Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine,
2Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, 200 Lothrop Street, University of Pittsburgh, Pittsburgh, PA, 15261,
3Department of Pediatric Nephrology, University of Virginia, Charlottesville, VA, 22908
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