Xiaoyang Qi

Ex vivo localization of the mouse saposin C activation region for acid beta-glucosidase.

Prosaposin: threshold rescue and analysis of the "neuritogenic" region in transgenic mice.

Phospholipid membrane interactions of saposin C: in situ atomic force microscopic study.

Phospholipid vesicle fusion induced by saposin C.

Saposin C is required for normal resistance of acid beta-glucosidase to proteolytic degradation.

Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.

Fusogenic domain and lysines in saposin C.

Direct AFM observation of saposin C-induced membrane domains in lipid bilayers: from simple to complex lipid mixtures.

Computational models for the helix tilt angle.

Saposin C-LBPA interaction in late-endosomes/lysosomes.

Mapping and analysis of the lytic and fusogenic domains of surfactant protein B.

Saposin C: neuronal effect and CNS delivery by liposomes.

Role of lysine residues in membrane anchoring of saposin C.

Structural changes in a binary mixed phospholipid bilayer of DOPG and DOPS upon saposin C interaction at acidic pH utilizing 31P and 2H solid-state NMR spectroscopy.

Spontaneously forming ellipsoidal phospholipid unilamellar vesicles and their interactions with helical domains of saposin C.

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules.

Investigating the interaction of saposin C with POPS and POPC phospholipids: a solid-state NMR spectroscopic study.

Controlled release mechanisms of spontaneously forming unilamellar vesicles.

Cancer-selective targeting and cytotoxicity by liposomal-coupled lysosomal saposin C protein.

Saposin C coupled lipid nanovesicles enable cancer-selective optical and magnetic resonance imaging.

Toll-like receptor 4 can recognize SapC-DOPS to stimulate macrophages to express several cytokines.

Saposin C coupled lipid nanovesicles specifically target arthritic mouse joints for optical imaging of disease severity.

Systemic delivery of SapC-DOPS has antiangiogenic and antitumor effects against glioblastoma.

Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinoma.

Targeting and cytotoxicity of SapC-DOPS nanovesicles in pancreatic cancer.

Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.

Pancreatic cancer: current standards, working towards a new therapeutic approach.

[MicroRNA target predicition based on SVM and the optimized feature set].