Erik M. M. Manders

Large-scale chromatin organization and the localization of proteins involved in gene expression in human cells.

Condensed chromatin domains in the mammalian nucleus are accessible to large macromolecules.

In vivo dynamics of chromatin-associated complex formation in mammalian nucleotide excision repair.

Imaging in situ protein-DNA interactions in the cell nucleus using FRET-FLIM.

Expression of effector gene SIX1 of Fusarium oxysporum requires living plant cells.

Spatially confined folding of chromatin in the interphase nucleus.

The nuclear protein Sge1 of Fusarium oxysporum is required for parasitic growth.

Increased plasticity of the nuclear envelope and hypermobility of telomeres due to the loss of A-type lamins.

Severe early life stress hampers spatial learning and neurogenesis, but improves hippocampal synaptic plasticity and emotional learning under high-stress conditions in adulthood.

Early maternal deprivation affects dentate gyrus structure and emotional learning in adult female rats.

Mass spectrometric quantification of the adaptations in the wall proteome of Candida albicans in response to ambient pH.

Models of the behaviour of (thermally stressed) microbial spores in foods: tools to study mechanisms of damage and repair.

Real-time visualization of heterotrimeric G protein Gq activation in living cells.

Repetitive disruptions of the nuclear envelope invoke temporary loss of cellular compartmentalization in laminopathies.

Live cell imaging of germination and outgrowth of individual bacillus subtilis spores; the effect of heat stress quantitatively analyzed with SporeTracker.

Re-scan confocal microscopy: scanning twice for better resolution.

Filamin A promotes dynamin-dependent internalization of hyperpolarization-activated cyclic nucleotide-gated type 1 (HCN1) channels and restricts Ih in hippocampal neurons.