Christiana Ruhrberg

Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis.

Mutations in dynein link motor neuron degeneration to defects in retrograde transport.

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia.

Neuronal defects in the hindbrain of Hoxa1, Hoxb1 and Hoxb2 mutants reflect regulatory interactions among these Hox genes.

Growing and shaping the vascular tree: multiple roles for VEGF.

Mapping nucleolar and spliceosome localization sequences of neuregulin1-beta3.

Neuropilin-1 is required for endothelial tip cell guidance in the developing central nervous system.

Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve.

Selective requirements for NRP1 ligands during neurovascular patterning.

Role of the neuropilin ligands VEGF164 and SEMA3A in neuronal and vascular patterning in the mouse.

Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells.

Blood vessel maturation and response to vascular-disrupting therapy in single vascular endothelial growth factor-A isoform-producing tumors.

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

Neuropilin 1 signaling guides neural crest cells to coordinate pathway choice with cell specification.

Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia.

Neuropilin ligands in vascular and neuronal patterning.

Neuropilin, you gotta let me know: should I stay or should I go?

Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction.

A double agent in cancer: deciphering macrophage roles in human tumors.

VEGF receptor signaling in vertebrate development.

VEGF in the nervous system.

In the beginning: Generating neural crest cell diversity.

Defective gonadotropin-releasing hormone neuron migration in mice lacking SEMA3A signalling through NRP1 and NRP2: implications for the aetiology of hypogonadotropic hypogonadism.

Neural crest origin of olfactory ensheathing glia.

Distinct macrophage phenotypes contribute to kidney injury and repair.

Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain.

VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm.

VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels.

Transcriptome analysis of embryonic mammary cells reveals insights into mammary lineage establishment.

The cytoplasmic domain of neuropilin 1 is dispensable for angiogenesis, but promotes the spatial separation of retinal arteries and veins.

The hormone of love attracts a partner for life.

Diverse roles for VEGF-A in the nervous system.

Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.

NRP1 and NRP2 cooperate to regulate gangliogenesis, axon guidance and target innervation in the sympathetic nervous system.

Emerging roles for semaphorins and VEGFs in synaptogenesis and synaptic plasticity.

NRP1 acts cell autonomously in endothelium to promote tip cell function during sprouting angiogenesis.

Neuropilin signalling in vessels, neurons and tumours.

The embryonic mouse hindbrain as a qualitative and quantitative model for studying the molecular and cellular mechanisms of angiogenesis.

Neurovascular development and links to disease.

The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis.

The cytoplasmic domain of neuropilin-1 regulates focal adhesion turnover.

Vascularisation is not necessary for gut colonisation by enteric neural crest cells.

Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis.

Neuropilin regulation of angiogenesis, arteriogenesis and vascular permeability.

Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells.

Neuropilin regulation of angiogenesis.

The mouse hindbrain: an in vivo model to analyze developmental angiogenesis.

VEGF189 binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain.

Neural crest cells in cardiovascular development.

Neural crest cell-derived VEGF promotes embryonic jaw extension.

Altered proliferative ability of neuronal progenitors in PlexinA1 mutant mice.

Dysfunctional SEMA3E signaling underlies gonadotropin-releasing hormone neuron deficiency in Kallmann syndrome.

NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells.

Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation.

Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis.

Vascularisation of the central nervous system.

Macrophage-Induced Blood Vessels Guide Schwann Cell-Mediated Regeneration of Peripheral Nerves.

The Embryonic Mouse Hindbrain and Postnatal Retina as In Vivo Models to Study Angiogenesis.

Myeloid-Derived Vascular Endothelial Growth Factor and Hypoxia-Inducible Factor Are Dispensable for Ocular Neovascularization--Brief Report.

NRP1 function and targeting in neurovascular development and eye disease.

2- and 6-O-sulfated proteoglycans have distinct and complementary roles in cranial axon guidance and motor neuron migration.

Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation.

Imatinib may be ABL to improve anti-angiogenic therapy.

Regulation of embryonic neurogenesis by germinal zone vasculature.

VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation.

Genetic specification of left-right asymmetry in the diaphragm muscles and their motor innervation.

VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels.

Vascular-Derived Vegfa Promotes Cortical Interneuron Migration and Proximity to the Vasculature in the Developing Forebrain.