Markku Varjosalo

Divergence of hedgehog signal transduction mechanism between Drosophila and mammals.

Identification of pathways regulating cell size and cell-cycle progression by RNAi.

Human receptors patched and smoothened partially transduce hedgehog signal when expressed in Drosophila cells.

Hedgehog signaling.

Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling.

Hedgehog: functions and mechanisms.

KSHV reactivation from latency requires Pim-1 and Pim-3 kinases to inactivate the latency-associated nuclear antigen LANA.

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.

FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex.

Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation.

Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.

Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung.

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

The protein interaction landscape of the human CMGC kinase group.

EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion.

Isolation, characterization and complete genome sequence of PhaxI: a phage of Escherichia coli O157 : H7.

Identification of candidate oncogenes in human colorectal cancers with microsatellite instability.

Protein secretome of moss plants (Physcomitrella patens) with emphasis on changes induced by a fungal elicitor.

Recognition of malondialdehyde-modified proteins by the C terminus of complement factor H is mediated via the polyanion binding site and impaired by mutations found in atypical hemolytic uremic syndrome.

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.