Stephen B. McMahon

Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats.

Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat.

P2X receptors and their role in female idiopathic detrusor instability.

Neurotrophin-3-mediated regeneration and recovery of proprioception following dorsal rhizotomy.

Chondroitinase ABC promotes functional recovery after spinal cord injury.

Molecular forms of NGF in human and rat neuropathic tissues: decreased NGF precursor-like immunoreactivity in human diabetic skin.

Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn.

BDNF: a neuromodulator in nociceptive pathways?

EphB receptors and ephrin-B ligands regulate spinal sensory connectivity and modulate pain processing.

The signaling components of sensory fiber transmission involved in the activation of ERK MAP kinase in the mouse dorsal horn.

Glial cell line-derived neurotrophic factor increases calcitonin gene-related peptide immunoreactivity in sensory and motoneurons in vivo.

Ultraviolet radiation-induced inflammation as a model for cutaneous hyperalgesia.

NGF and GDNF ameliorate the increase in ATF3 expression which occurs in dorsal root ganglion cells in response to peripheral nerve injury.

Conditioning injury-induced spinal axon regeneration fails in interleukin-6 knock-out mice.

Plasticity of pain signaling: role of neurotrophic factors exemplified by acid-induced pain.

Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord.

Neurotrophic influences on neuropathic pain.

Acid-induced pain and its modulation in humans.

Conditioning injury-induced spinal axon regeneration requires signal transducer and activator of transcription 3 activation.

Increased spinal cord phosphorylation of extracellular signal-regulated kinases mediates micturition overactivity in rats with chronic bladder inflammation.

Regulation of neuropilin 1 by spinal cord injury in adult rats.

Immune and glial cell factors as pain mediators and modulators.

Activity-dependent phosphorylation of Akt/PKB in adult DRG neurons.

P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP.

TrkB expression and phospho-ERK activation by brain-derived neurotrophic factor in rat spinothalamic tract neurons.

Inhibition of ERK phosphorylation decreases nociceptive behaviour in monoarthritic rats.

Role of the immune system in chronic pain.

Assessing behavioural function following a pyramidotomy lesion of the corticospinal tract in adult mice.

Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord.

Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain.

ATF3 expression in L4 dorsal root ganglion neurons after L5 spinal nerve transection.

A clonal cell line from immortalized olfactory ensheathing glia promotes functional recovery in the injured spinal cord.

Reversal of neurochemical changes and pain-related behavior in a model of neuropathic pain using modified lentiviral vectors expressing GDNF.

Spinal ERK activation contributes to the regulation of bladder function in spinal cord injured rats.

Role of spinal microglia in rat models of peripheral nerve injury and inflammation.

Increasingly irritable and close to tears: TRPA1 in inflammatory pain.

Neurotrophins: mediators and modulators of pain.

Spinal cord repair strategies: why do they work?

Rapid co-release of interleukin 1beta and caspase 1 in spinal cord inflammation.

Lentiviral vector expressing retinoic acid receptor beta2 promotes recovery of function after corticospinal tract injury in the adult rat spinal cord.

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

Artemin has potent neurotrophic actions on injured C-fibres.

Pharmacological, behavioural and mechanistic analysis of HIV-1 gp120 induced painful neuropathy.

The activation of the ERK pathway contributes to the spinal c-fos expression observed after noxious bladder stimulation.

Pathophysiology of peripheral neuropathic pain: immune cells and molecules.

Characterization of rodent models of HIV-gp120 and anti-retroviral-associated neuropathic pain.

Heritability of responses to painful stimuli in women: a classical twin study.

Transplanted neural progenitor cells survive and differentiate but achieve limited functional recovery in the lesioned adult rat spinal cord.

Modulation of acid-sensing ion channel activity by nitric oxide.

Microchannels as axonal amplifiers.

Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions.

CCL2 is a key mediator of microglia activation in neuropathic pain states.

Comparison of dorsal root ganglion gene expression in rat models of traumatic and HIV-associated neuropathic pain.

Ultraviolet-B induced inflammation of human skin: characterisation and comparison with traditional models of hyperalgesia.

Mice lacking acid-sensing ion channels (ASIC) 1 or 2, but not ASIC3, show increased pain behaviour in the formalin test.

Effects of Etanercept and Minocycline in a rat model of spinal cord injury.

Chondroitinase ABC-mediated plasticity of spinal sensory function.

Expression of the regeneration-associated protein SPRR1A in primary sensory neurons and spinal cord of the adult mouse following peripheral and central injury.

The yellow fluorescent protein (YFP-H) mouse reveals neuroprotection as a novel mechanism underlying chondroitinase ABC-mediated repair after spinal cord injury.

Microchannel electrodes for recording and stimulation: in vitro evaluation.

Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.

Future treatment strategies for neuropathic pain.

Current challenges in glia-pain biology.

Identification of perineal sensory neurons activated by innocuous heat.

P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide.

Endogenous purinergic control of bladder activity via presynaptic P2X3 and P2X2/3 receptors in the spinal cord.

Ultraviolet-B-induced mechanical hyperalgesia: A role for peripheral sensitisation.

Neural progenitors promote axon growth in vitro and ex vivo but not following injury.

Delayed treatment with chondroitinase ABC reverses chronic atrophy of rubrospinal neurons following spinal cord injury.

Perturbing PSD-95 interactions with NR2B-subtype receptors attenuates spinal nociceptive plasticity and neuropathic pain.

New molecules for the treatment of pain.

CXCL5 mediates UVB irradiation-induced pain.

Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat.

Conduction failure following spinal cord injury: functional and anatomical changes from acute to chronic stages.

A regenerative microchannel neural interface for recording from and stimulating peripheral axons in vivo.

Chronic pain: emerging evidence for the involvement of epigenetics.

Understanding chronic inflammatory and neuropathic pain.

Chondroitinase ABC promotes plasticity of spinal reflexes following peripheral nerve injury.

Sensory neuron downregulation of the Kv9.1 potassium channel subunit mediates neuropathic pain following nerve injury.

Genes contributing to pain sensitivity in the normal population: an exome sequencing study.

Genes and epigenetic processes as prospective pain targets.

Characterisation and mechanisms of bradykinin-evoked pain in man using iontophoresis.

HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain.

Axonal neuregulin 1 is a rate limiting but not essential factor for nerve remyelination.

Chronic cough and pain: Janus faces in sensory neurobiology?

PainNetworks: a web-based resource for the visualisation of pain-related genes in the context of their network associations.

Chemokines as peripheral pain mediators.

A microchannel neuroprosthesis for bladder control after spinal cord injury in rat.

Chemokine expression in peripheral tissues from the monosodium iodoacetate model of chronic joint pain.

Kv2 dysfunction after peripheral axotomy enhances sensory neuron responsiveness to sustained input.

Probing functional properties of nociceptive axons using a microfluidic culture system.

Synthesis of lipid mediators during UVB-induced inflammatory hyperalgesia in rats and mice.

Opening paths to novel analgesics: the role of potassium channels in chronic pain.

A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat.

Pain vulnerability: a neurobiological perspective.

Botulinum toxin-A treatment reduces human mechanical pain sensitivity and mechanotransduction.

Molecular mechanisms underlying the enhanced analgesic effect of oxycodone compared to morphine in chemotherapy-induced neuropathic pain.

Genome-wide transcriptional profiling of skin and dorsal root ganglia after ultraviolet-B-induced inflammation.

Null mutation in SCN9A in which noxious stimuli can be detected in the absence of pain.

Defining the nociceptor transcriptome.