Jochen Steppan

Knockdown of arginase I restores NO signaling in the vasculature of old rats.

Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism.

Effects of verum acupuncture compared to placebo acupuncture on quantitative EEG and heart rate variability in healthy volunteers.

The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation.

Central sympatholytics prolong survival in experimental sepsis.

Cell death serum biomarkers are early predictors for survival in severe septic patients with hepatic dysfunction.

Sepsis and major abdominal surgery lead to flaking of the endothelial glycocalix.

β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation.

Redox responses in patients with sepsis: high correlation of thioredoxin-1 and macrophage migration inhibitory factor plasma levels.

Macrophage migration inhibitory factor (MIF) and manganese superoxide dismutase (MnSOD) as early predictors for survival in patients with severe sepsis or septic shock.

Pheochromocytoma presenting as acute heart failure leading to cardiogenic shock and multiorgan failure.

Vascular stiffness and increased pulse pressure in the aging cardiovascular system.

Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels.

Upregulation of arginase-II contributes to decreased age-related myocardial contractile reserve.

Chronic oral administration of the arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) improves erectile function in aged rats.

Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness.

Vasopressin-mediated enhancement of adrenergic vasoconstriction involves both the tyrosine kinase and the protein kinase C pathways.

Patient safety reporting systems: sustained quality improvement using a multidisciplinary team and "good catch" awards.

Interleukin 10 knockout frail mice develop cardiac and vascular dysfunction with increased age.

Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice.

Development of novel arginase inhibitors for therapy of endothelial dysfunction.

Contribution of arginase activation to vascular dysfunction in cigarette smoking.

A protocol-driven approach to early extubation after heart surgery.

Exercise, vascular stiffness, and tissue transglutaminase.

Complications of Catheter-Based Electrophysiology Procedures in Adults with Congenital Heart Disease: A National Analysis.

Melanopsin mediates light-dependent relaxation in blood vessels.