David R. Jones

The impact of the lung allocation score on short-term transplantation outcomes: a multicenter study.

Identification of small lung nodules: technique of radiotracer-guided thoracoscopic biopsy.

A phase I and pharmacokinetic trial of erlotinib in combination with weekly docetaxel in patients with taxane-naive malignancies.

Cell culture conditions potentiate differences in the response to ionising radiation of peripheral blood leukocytes isolated from breast cancer patients and healthy subjects.

Flying and dying in WWI: British aircrew losses and the origins of U.S. military aviation medicine.

Relative survival: what can cardiovascular disease learn from cancer?

Effects of induction immunosuppression regimen on acute rejection, bronchiolitis obliterans, and survival after lung transplantation.

Does positron emission tomography prevent nontherapeutic pulmonary resections for clinical stage IA lung cancer?

Tracheal compression delays alveolar collapse during deep diving in marine mammals.

Quantification of vincristine and its major metabolite in human plasma by high-performance liquid chromatography/tandem mass spectrometry.

Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry.

Sarcoma of the bladder with metastasis to the left ventricle.

Radiotracer-guided thoracoscopic resection is a cost-effective technique for the evaluation of subcentimeter pulmonary nodules.

VATS lobectomy is better than open thoracotomy: what is the evidence for short-term outcomes?

Differential recovery from exercise and hypoxia exposure measured using 31P- and 1H-NMR in white muscle of the common carp Cyprinus carpio.

Prediction of the effect of erythromycin, diltiazem, and their metabolites, alone and in combination, on CYP3A4 inhibition.

Relevance of the capacity of phosphorylated fructose to scavenge the hydroxyl radical.

Reproducibility of interfraction lung motion probability distribution function using dynamic MRI: statistical analysis.

Metabolic costs of foraging and the management of O2 and CO2 stores in Steller sea lions.

Measuring the quality of surgical outcomes in general thoracic surgery: should surgical volume be used to direct patient referrals?

Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis and correlates with improved patient survival in non-small cell lung cancer.

Correlations between selected tumor markers and fluorodeoxyglucose maximal standardized uptake values in esophageal cancer.

Fluorodeoxyglucose positron emission tomography and tumor marker expression in non-small cell lung cancer.

A bilobed thoracic outlet mass: options for resection.

Methods for the determination of the mass of nuclear PtdIns4P, PtdIns5P, and PtdIns(4,5)P2.

Assaying endogenous phosphatidylinositol-4-phosphate 5-kinase (PIP5K) activities.

Does reperfusion injury still cause significant mortality after lung transplantation?

Genetic markers of mediastinal tumors.

Evidence synthesis as the key to more coherent and efficient research.

Semiphysiologically based pharmacokinetic models for the inhibition of midazolam clearance by diltiazem and its major metabolite.

Interspecies extrapolation in environmental exposure standard setting: A Bayesian synthesis approach.

Validation of the use of doubly labeled water for estimating metabolic rate in the green turtle (Chelonia mydas L.): a word of caution.

Basaloid squamous cell carcinoma of the esophagus: assessment for high-risk human papillomavirus and related molecular markers.

Inhibition of CYP3A by erythromycin: in vitro-in vivo correlation in rats.

Prognostic value of admission blood glucose concentration and diabetes diagnosis on survival after acute myocardial infarction: results from 4702 index cases in routine practice.

Predicted risk of mortality models: surgeons need to understand limitations of the University HealthSystem Consortium models.

Phase I trial of intrapleural docetaxel administered through an implantable catheter in subjects with a malignant pleural effusion.

Preoperative embolization of Castleman's disease using microspheres.

Lipid status, anti-oxidant enzyme defence and haemoglobin content in the blood of long-term clozapine-treated schizophrenic patients.

A phase I dose escalation and pharmacokinetic study of vatalanib (PTK787/ZK 222584) in combination with paclitaxel in patients with advanced solid tumors.

Rosai-Dorfman disease presenting as a pulmonary artery mass.

A thoracic surgeon-directed tobacco cessation intervention.

Transplant pneumonectomy in a patient with an acutely thrombosed allograft.

Video-assisted thoracic surgery versus open lobectomy for lung cancer: a secondary analysis of data from the American College of Surgeons Oncology Group Z0030 randomized clinical trial.

Bioavailability and catalytic properties of copper and iron for Fenton chemistry in human cerebrospinal fluid.

Esophageal inflammatory myofibroblastic tumor sampled by EUS-FNA.

Efavirenz primary and secondary metabolism in vitro and in vivo: identification of novel metabolic pathways and cytochrome P450 2A6 as the principal catalyst of efavirenz 7-hydroxylation.

Combined proteasome and histone deacetylase inhibition attenuates epithelial-mesenchymal transition through E-cadherin in esophageal cancer cells.

Donor factors are associated with bronchiolitis obliterans syndrome after lung transplantation.

The legends behind cardiothoracic surgical instruments.

The European and American use of exploratory approaches for first-in-human studies.

Correlation analysis confirms differences in antioxidant defence in the blood of types I and II schizophrenic male patients treated with anti-psychotic medication.

BRMS1 transcriptional repression correlates with CpG island methylation and advanced pathological stage in non-small cell lung cancer.

Size matters: a comparison of T1 and T2 peripheral non-small-cell lung cancers treated with stereotactic body radiation therapy (SBRT).

Different roles of radical scavengers--ascorbate and urate in the cerebrospinal fluid of amyotrophic lateral sclerosis patients.

Empirical assessment suggests that existing evidence could be used more fully in designing randomized controlled trials.

Direct regulation of striated muscle myosins by nitric oxide and endogenous nitrosothiols.

Donor age is associated with chronic allograft vasculopathy after adult heart transplantation: implications for donor allocation.

Primary payer status affects mortality for major surgical operations.

Clinicians' views on the feasibility of surgical randomized trials in urogynecology: results of a questionnaire survey.

Multigene expression-based predictors for sensitivity to Vorinostat and Velcade in non-small cell lung cancer.

STS database risk models: predictors of mortality and major morbidity for lung cancer resection.

Number of lymph nodes harvested from a mediastinal lymphadenectomy: results of the randomized, prospective American College of Surgeons Oncology Group Z0030 trial.

Drag-based 'hovering' in ducks: the hydrodynamics and energetic cost of bottom feeding.

Routine educational outcome measures in health studies: Key Stage 1 in the ORACLE Children Study follow-up of randomised trial cohorts.

Phosphatidylinositol 5-phosphate links dehydration stress to the activity of ARABIDOPSIS TRITHORAX-LIKE factor ATX1.

Comparative analysis of showering protocols for mass-casualty decontamination.

Helical tomotherapy-based STAT stereotactic body radiation therapy: Dosimetric evaluation for a real-time SBRT treatment planning and delivery program.

Behaviour and physiology: the thermal strategy of leatherback turtles.

Seasonal variation influences outcomes following lung cancer resections.

Existing general population models inaccurately predict lung cancer risk in patients referred for surgical evaluation.

Relevance of the ability of fructose 1,6-bis(phosphate) to sequester ferrous but not ferric ions.

Bronchiolitis obliterans syndrome occurs earlier in the post-lung allocation score era.

Randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with N0 or N1 (less than hilar) non-small cell carcinoma: results of the American College of Surgery Oncology Group Z0030 Trial.

Depletion of tissue plasminogen activator attenuates lung ischemia-reperfusion injury via inhibition of neutrophil extravasation.

Humanized bone marrow mouse model as a preclinical tool to assess therapy-mediated hematotoxicity.

Temperature-dependent regulation of blood distribution in snakes.

A positive return on investment: research funding by the Thoracic Surgery Foundation for Research and Education (TSFRE).

A pilot study of the impact of genotype on nifedipine pharmacokinetics when used as a tocolytic.

To RCT or not to RCT: deciding when 'more evidence is needed' for public health policy and practice.

Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth.

Gender, race, and socioeconomic status affects outcomes after lung cancer resections in the United States.

The impact of adjuvant brachytherapy with sublobar resection on pulmonary function and dyspnea in high-risk patients with operable disease: preliminary results from the American College of Surgeons Oncology Group Z4032 trial.

Providing the results of research to participants: a mixed-method study of the benefits and challenges of a consultative approach.

Ligation of the left aorta in alligators affects acid-base balance: a role for the R→L shunt.

Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials.

Phosphoinositide phosphatase SHIP-1 regulates apoptosis induced by edelfosine, Fas ligation and DNA damage in mouse lymphoma cells.

S-nitrosoglutathione reductase in human lung cancer.

Measuring energy expenditure in sub-adult and hatchling sea turtles via accelerometry.

Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis.

Characterization of novel synthesized small molecular compounds against non-small cell lung cancer.

Thirty- and ninety-day outcomes after sublobar resection with and without brachytherapy for non-small cell lung cancer: results from a multicenter phase III study.

Intraoperative factors and the risk of respiratory complications after pneumonectomy.

The genetic component of the forced diving bradycardia response in mammals.

Occult metastases in lymph nodes predict survival in resectable non-small-cell lung cancer: report of the ACOSOG Z0040 trial.

Ecotoxicological assessment of a polyelectrolyte flocculant.

Geographic distance between donor and recipient does not influence outcomes after lung transplantation.

Subcutaneous 5-azacitidine treatment of naturally occurring canine urothelial carcinoma: a novel epigenetic approach to human urothelial carcinoma drug development.

A diagnostic consideration for all ages: pseudoachalasia in a 22-year-old male.

Impaired neural development in a zebrafish model for Lowe syndrome.

Divergent functions of the myotubularin (MTM) homologs AtMTM1 and AtMTM2 in Arabidopsis thaliana: evolution of the plant MTM family.

Nuclear phosphoinositides: location, regulation and function.

What works, for whom, in what contexts, who needs to know, and how will they use the information (if at all): a response.

Tumor recurrence after complete resection for non-small cell lung cancer.

The Society of Thoracic Surgeons General Thoracic Surgery Database: establishing generalizability to national lung cancer resection outcomes.

Pathologic lymph node ratio is a predictor of survival in esophageal cancer.

Methodology and reporting of systematic reviews and meta-analyses of observational studies in psychiatric epidemiology: systematic review.

Invited commentary.

Differences in reported esophageal cancer resection outcomes between national clinical and administrative databases.

Hospital procedure volume should not be used as a measure of surgical quality.

Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF-κB acetylation and transcription.

Phase I trial of induction histone deacetylase and proteasome inhibition followed by surgery in non-small-cell lung cancer.

Survival after lung transplant for coal workers' pneumoconiosis.

Resource requirements of the Pacific leatherback turtle population.

A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes.

Invited commentary.

Pulmonary resections performed at hospitals with thoracic surgery residency programs have superior outcomes.

Invited commentary.

Highly treated mine waters may require major ion addition before environmental release.

Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress.

A regulatory perspective of clinical trial applications for biological products with particular emphasis on Advanced Therapy Medicinal Products (ATMPs).

Pharmacokinetic and pharmacodynamic alterations in the Roux-en-Y gastric bypass recipients.

PtdIns5P is an oxidative stress-induced second messenger that regulates PKB activation.

BRMS1 suppresses lung cancer metastases through an E3 ligase function on histone acetyltransferase p300.

In vivo DPP-4 inhibition to enhance engraftment of single-unit cord blood transplants in adults with hematological malignancies.

Integrated therapeutic approaches in the treatment of locally advanced non-small cell lung cancer.

Hydrogen peroxide in adaptation.

Association of Inhalation Toxicologists' (AIT) review of regulatory aspects for inhalation toxicology studies.

Small-molecule inhibition of the uPAR·uPA interaction: synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis.

Use of Dried Plasma Spots for the Quantification of Iothalamate in Clinical Studies.

Strategic regulatory approaches for the qualification of a biomarker assay for safety use.

Influence of hemodialysis on clinical outcomes after lung transplantation.

Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila development.

Role of phosphatidylinositol 5-phosphate 4-kinase α in zebrafish development.

PtdIns5P and Pin1 in oxidative stress signaling.

Induction chemoradiotherapy and surgery for esophageal cancer: survival benefit with downstaging.

Special treatment issues in non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.

Measurement of phosphoinositides in the zebrafish Danio rerio.

Ten-year experience on 644 patients undergoing single-port (uniportal) video-assisted thoracoscopic surgery.

Long-term satisfaction and medication dependence after antireflux surgery.

Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in response to oxidative stress and energy restriction.

Reply: To PMID 22621876.

NF-κB regulates mesenchymal transition for the induction of non-small cell lung cancer initiating cells.

Lymph node ratio predicts recurrence and survival after R0 resection for non-small cell lung cancer.

Epigenetic coordination of signaling pathways during the epithelial-mesenchymal transition.

Teaching video-assisted thoracic surgery (VATS) lobectomy.

Nuclear phosphoinositides and their impact on nuclear functions.

Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression.

Leiomyoma presenting as a massive calcified circumferential esophageal mass.

Marginal pulmonary function should not preclude lobectomy in selected patients with non-small cell lung cancer.

Hemodialysis does not alter in vitro hepatic CYP3A4 and CYP2D6 metabolic activity in uremic serum.

Accuracy of fluorodeoxyglucose-positron emission tomography within the clinical practice of the American College of Surgeons Oncology Group Z4031 trial to diagnose clinical stage I non-small cell lung cancer.

Predictors of hospital discharge to an extended care facility after major general thoracic surgery.

Inhibition of breast cancer metastasis suppressor 1 promotes a mesenchymal phenotype in lung epithelial cells that express oncogenic K-RasV12 and loss of p53.

The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation.

Impact of brachytherapy on local recurrence rates after sublobar resection: results from ACOSOG Z4032 (Alliance), a phase III randomized trial for high-risk operable non-small-cell lung cancer.

Estimating smoking prevalence in general practice using data from the Quality and Outcomes Framework (QOF).

Second primary lung cancers: smokers versus nonsmokers after resection of stage I lung adenocarcinoma.

Network meta-analysis of multiple outcome measures accounting for borrowing of information across outcomes.

Comprehensive long-term care of patients with lung cancer: development of a novel thoracic survivorship program.

Extracellular iron diminishes anticancer effects of vitamin C: an in vitro study.

Differences in patterns of recurrence in early-stage versus locally advanced non-small cell lung cancer.

Predictors of early recurrence for node-negative t1 to t2b non-small cell lung cancer.

Thirty-day mortality underestimates the risk of early death after major resections for thoracic malignancies.

Recent advances and clinical implications of the micropapillary histological subtype in lung adenocarcinomas.

Response to "what constitutes scientific justification for inclusion of recovery assessment in pre-clinical studies supporting first time in man (FTIM)?" Sally Robinson and Ruth Roberts, Drug Safety and Metabolism, AstraZeneca, Alderley Park, Macclesfield, UK.

Intraoperative near-infrared fluorescence imaging as an adjunct to robotic-assisted minimally invasive esophagectomy.

A phase II study of medroxyprogesterone acetate in patients with hormone receptor negative metastatic breast cancer: translational breast cancer research consortium trial 007.

Validation of the new IASLC/ATS/ERS lung adenocarcinoma classification: a surgeon's perspective.

Implementing the new IASLC/ATS/ERS classification of lung adenocarcinomas: results from international and Chinese cohorts.

Comment on He et al., VATS bronchial sleeve resection.

Loss of BRMS1 promotes a mesenchymal phenotype through NF-κB-dependent regulation of Twist1.

Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity.

Activin upregulation by NF-κB is required to maintain mesenchymal features of cancer stem-like cells in non-small cell lung cancer.

Utility of mediastinoscopy in clinical stage I lung cancers at risk for occult mediastinal nodal metastases.

Analysis of longitudinal quality-of-life data in high-risk operable patients with lung cancer: results from the ACOSOG Z4032 (Alliance) multicenter randomized trial.

Nicotine and cotinine exposure from electronic cigarettes: a population approach.

Where have all the clinical trials gone?

Thymic carcinoma outcomes and prognosis: results of an international analysis.

The new IASLC-ATS-ERS lung adenocarcinoma classification: what the surgeon should know.

Tumoral CD10 Expression Correlates with Aggressive Histology and Prognosis in Patients with Malignant Pleural Mesothelioma.

Tumor Spread through Air Spaces is an Important Pattern of Invasion and Impacts the Frequency and Location of Recurrences after Limited Resection for Small Stage I Lung Adenocarcinomas.

Solutions to intraoperative wound classification miscoding in a subset of American College of Surgeons National Surgical Quality Improvement Program patients.

Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies.

PIP4K and the role of nuclear phosphoinositides in tumour suppression.

Small RNA sequencing for profiling microRNAs in long-term preserved formalin-fixed and paraffin-embedded non-small cell lung cancer tumor specimens.

Tumor Budding Correlates with Protumor Immune Microenvironment and is an Independent Prognostic Factor for Recurrence of Stage I Lung Adenocarcinoma.

Comparing surgical infections in National Surgical Quality Improvement Project and an Institutional Database.

The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output.

Reevaluation and Reclassification of Resected Lung Carcinomas Originally Diagnosed as Squamous Cell Carcinoma Using Immunohistochemical Analysis.

The effectiveness of different interventions to promote poison prevention behaviours in households with children: a network meta-analysis.

Results of the national lung cancer screening trial: where are we now?

In Vivo Assessment of the Metabolic Activity of CYP2D6 Diplotypes and Alleles.

Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1.

FDG Positron Emission Tomography and Computed Tomography Demonstration of Carcinoma Arising in an Epiphrenic Diverticulum.

The tumor immune microenvironment in octogenarians with stage I non-small cell lung cancer.

Resection of Primary and Secondary Tumors of the Sternum: An Analysis of Prognostic Variables.

A framework for the in vitro evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues.

Esophageal adenocarcinoma: Wanted-new models and better targets.