Paul R. Copeland

Purification and analysis of selenocysteine insertion sequence-binding protein 2.

Mechanism and regulation of selenoprotein synthesis.

Regulation of gene expression by stop codon recoding: selenocysteine.

Efficiency of mammalian selenocysteine incorporation.

Making sense of nonsense: the evolution of selenocysteine usage in proteins.

Characterization of the SECIS binding protein 2 complex required for the co-translational insertion of selenocysteine in mammals.

Selenoprotein expression is regulated at multiple levels in prostate cells.

The L7Ae RNA binding motif is a multifunctional domain required for the ribosome-dependent Sec incorporation activity of Sec insertion sequence binding protein 2.

Functional analysis of the interplay between translation termination, selenocysteine codon context, and selenocysteine insertion sequence-binding protein 2.

Analysis of Saccharomyces cerevisiae null allele strains identifies a larger role for DNA damage versus oxidative stress pathways in growth inhibition by selenium.

A novel protein domain induces high affinity selenocysteine insertion sequence binding and elongation factor recruitment.

Genome-wide screen of Saccharomyces cerevisiae null allele strains identifies genes involved in selenomethionine resistance.

Evolutionary history of selenocysteine incorporation from the perspective of SECIS binding proteins.

Threading the needle: getting selenocysteine into proteins.

The efficiency of selenocysteine incorporation is regulated by translation initiation factors.

A birth-to-death view of mRNA from the RNA recognition motif perspective.

SECIS binding protein 2 alters the conformational dynamics of residues involved in tRNA accommodation in 80S ribosomes.