Padma-Sheela Jayaraman

The transcriptional repressor protein PRH interacts with the proteasome.

The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cells.

Purification and characterisation of the PRH homeodomain: Removal of the N-terminal domain of PRH increases the PRH homeodomain-DNA interaction.

Oligomerisation of the developmental regulator proline rich homeodomain (PRH/Hex) is mediated by a novel proline-rich dimerisation domain.

PRH/Hex: an oligomeric transcription factor and multifunctional regulator of cell fate.

The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors.

DNA wrapping and distortion by an oligomeric homeodomain protein.

CK2 phosphorylation of the PRH/Hex homeodomain functions as a reversible switch for DNA binding.

Activation of proteinase-activated receptor 2 stimulates soluble vascular endothelial growth factor receptor 1 release via epidermal growth factor receptor transactivation in endothelial cells.

PRH/Hhex controls cell survival through coordinate transcriptional regulation of vascular endothelial growth factor signaling.

DNA compaction by the higher-order assembly of PRH/Hex homeodomain protein oligomers.