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Stem Cells & Cancer Group,
Molecular Pathology Program,
Stem Cells & Cancer Group, Molecular Pathology Program
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Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.
The Journal of cell biology Feb, 2008 | Pubmed ID: 18268105
Introduction of a novel pathway for IAA biosynthesis to rhizobia alters vetch root nodule development.
Archives of microbiology Jul, 2008 | Pubmed ID: 18415080
Qualitative and quantitative proteomic profiling of cripto(-/-) embryonic stem cells by means of accurate mass LC-MS analysis.
Journal of proteome research Feb, 2009 | Pubmed ID: 19152270
Effects of indole-3-acetic acid on Sinorhizobium meliloti survival and on symbiotic nitrogen fixation and stem dry weight production.
Applied microbiology and biotechnology Jun, 2009 | Pubmed ID: 19343341
G protein-coupled receptor APJ and its ligand apelin act downstream of Cripto to specify embryonic stem cells toward the cardiac lineage through extracellular signal-regulated kinase/p70S6 kinase signaling pathway.
Circulation research Jul, 2009 | Pubmed ID: 19574549
Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells.
The American journal of pathology Nov, 2009 | Pubmed ID: 19834060
Lack of sik1 in mouse embryonic stem cells impairs cardiomyogenesis by down-regulating the cyclin-dependent kinase inhibitor p57kip2.
PloS one , 2010 | Pubmed ID: 20140255
Pancreatic cancer stem cells - update and future perspectives.
Molecular oncology Oct, 2010 | Pubmed ID: 20580623
A small synthetic cripto blocking Peptide improves neural induction, dopaminergic differentiation, and functional integration of mouse embryonic stem cells in a rat model of Parkinson's disease.
Stem cells (Dayton, Ohio) Aug, 2010 | Pubmed ID: 20641036
Pancreatic cancer stem cells: new insights and perspectives.
Journal of gastroenterology Aug, 2011 | Pubmed ID: 21698355
Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.
Cell stem cell Nov, 2011 | Pubmed ID: 22056140
Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness.
Cell cycle (Georgetown, Tex.) Apr, 2012 | Pubmed ID: 22421149
Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2012 | Pubmed ID: 23129614
Metformin targets the metabolic achilles heel of human pancreatic cancer stem cells.
PloS one , 2013 | Pubmed ID: 24204632
Intracellular autofluorescence: a biomarker for epithelial cancer stem cells.
Nature methods Nov, 2014 | Pubmed ID: 25262208
Stromal gene expression defines poor-prognosis subtypes in colorectal cancer.
Nature genetics Apr, 2015 | Pubmed ID: 25706628
The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells.
Gut Apr, 2015 | Pubmed ID: 25887381
Spanish National Cancer Research Center
Institute for Research in Biomedicine (IRB Barcelona)
Enza Lonardo1,2,
Michele Cioffi1,
Patricia Sancho1,3,
Shanthini Crusz3,
Christopher Heeschen1,3
1Stem Cells & Cancer Group, Molecular Pathology Program, Spanish National Cancer Research Center,
2, Institute for Research in Biomedicine (IRB Barcelona),
3Center for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London
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