Raymond Chuen-Chung Chang

Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2alpha in neuronal degeneration.

BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis.

Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity.

Reduction of calcium release from the endoplasmic reticulum could only provide partial neuroprotection against beta-amyloid peptide toxicity.

Modulation of calcium/calmodulin kinase-II provides partial neuroprotection against beta-amyloid peptide toxicity.

Characterization of polysaccharides from the flowers of Nerium indicum and their neuroprotective effects.

Immune modulatory effects of Prunella vulgaris L.

Stable expression of EBERs in immortalized nasopharyngeal epithelial cells confers resistance to apoptotic stress.

Neuroprotective effects of anti-aging oriental medicine Lycium barbarum against beta-amyloid peptide neurotoxicity.

Immune modulatory effects of Prunella vulgaris L. on monocytes/macrophages.

Novel neuroprotective effects of the aqueous extracts from Verbena officinalis Linn.

Beta-amyloid peptides induces neuronal apoptosis via a mechanism independent of unfolded protein responses.

Cytoprotective effects of Lycium barbarum against reducing stress on endoplasmic reticulum.

Neuroprotective effects of Lycium barbarum Lynn on protecting retinal ganglion cells in an ocular hypertension model of glaucoma.

New polysaccharide from Nerium indicum protects neurons via stress kinase signaling pathway.

Significance of molecular signaling for protein translation control in neurodegenerative diseases.

Characterizing the neuroprotective effects of alkaline extract of Lycium barbarum on beta-amyloid peptide neurotoxicity.

Characterization of the effects of anti-aging medicine Fructus lycii on beta-amyloid peptide neurotoxicity.

Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far?

Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum.

Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity.

Effects of all-trans-retinoic acid on human SH-SY5Y neuroblastoma as in vitro model in neurotoxicity research.

Low molecular weight Abeta induces collapse of endoplasmic reticulum.

Protective effects of pinostilbene, a resveratrol methylated derivative, against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.

Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons.

Calcium dysregulation in Alzheimer's disease: from mechanisms to therapeutic opportunities.

Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model.

Could PKR inhibition modulate human neurodegeneration?

Anti-aging herbal medicine--how and why can they be used in aging-associated neurodegenerative diseases?

Modulation of neuroimmune responses on glia in the central nervous system: implication in therapeutic intervention against neuroinflammation.

Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight β-amyloid peptide.

A pro-drug of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) prevents differentiated SH-SY5Y cells from toxicity induced by 6-hydroxydopamine.

Erratum: Modulation of microglia by Wolfberry on the survival of retinal ganglion cells in a rat ocular hypertension model.

Modulation of morphological changes of microglia and neuroprotection by monocyte chemoattractant protein-1 in experimental glaucoma.

Transcriptional regulation of human FE65, a ligand of Alzheimer's disease amyloid precursor protein, by Sp1.

Neuroprotective effects of polysaccharides from wolfberry, the fruits of Lycium barbarum, against homocysteine-induced toxicity in rat cortical neurons.

Up-regulation of crystallins is involved in the neuroprotective effect of wolfberry on survival of retinal ganglion cells in rat ocular hypertension model.

The putative neurodegenerative links between depression and Alzheimer's disease.

Beneficial effects of cinnamon proanthocyanidins on the formation of specific advanced glycation endproducts and methylglyoxal-induced impairment on glucose consumption.

Modulation of mitochondrial calcium as a pharmacological target for Alzheimer's disease.

Sulfur-containing constituents and one 1H-pyrrole-2-carboxylic acid derivative from pineapple [Ananas comosus (L.) Merr.] fruit.

Light deprivation induces depression-like behavior and suppresses neurogenesis in diurnal mongolian gerbil (Meriones unguiculatus).

Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury.

Drug discovery from Chinese medicine against neurodegeneration in Alzheimer's and vascular dementia.

Neurodegeneration of the retina in mouse models of Alzheimer's disease: what can we learn from the retina?

Endoplasmic Reticulum Stress Induces Tau Pathology and Forms a Vicious Cycle: Implication in Alzheimer's Disease Pathogenesis.

Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation.

From small to big molecules: how do we prevent and delay the progression of age-related neurodegeneration?

Neuropathology of cigarette smoking.

Investigating degeneration of the retina in young and aged tau P301L mice.

Sickness: From the focus on cytokines, prostaglandins, and complement factors to the perspectives of neurons.

Editorial: Bioactive Small Molecules in Regulating Inflammation and Metabolic Disorder.

Bringing CLARITY to the human brain: visualization of Lewy pathology in three dimensions.

PKR deficiency alters E. coli-induced sickness behaviors but does not exacerbate neuroimmune responses or bacterial load.

Evidence of the impact of systemic inflammation on neuroinflammation from a non-bacterial endotoxin animal model.

Silica nanoparticles induce neurodegeneration-like changes in behavior, neuropathology, and affect synapse through MAPK activation.

Varenicline reduces DNA damage, tau mislocalization and post surgical cognitive impairment in aged mice.

Palmitate and Stearate are Increased in the Plasma in a 6-OHDA Model of Parkinson's Disease.

The beneficial effects of physical exercise in the brain and related pathophysiological mechanisms in neurodegenerative diseases.