Paul D. Adams

Molecular dynamics applied to X-ray structure refinement.

Alpha(IIb)beta(3) 整合素的跨膜信号转导。

Intramolecular quenching of tryptophan fluorescence by the peptide bond in cyclic hexapeptides.

PHENIX: building new software for automated crystallographic structure determination.

Fluorescence of cis-1-amino-2-(3-indolyl)cyclohexane-1-carboxylic acid: a single tryptophan chi(1) rotamer model.

Computational aspects of high-throughput crystallographic macromolecular structure determination.

High-resolution structure of RNase P protein from Thermotoga maritima.

X-ray crystallographic and kinetic studies of human sorbitol dehydrogenase.

Role of the gamma-phosphate of ATP in triggering protein folding by GroEL-GroES: function, structure and energetics.

Recent developments in the PHENIX software for automated crystallographic structure determination.

Crystal structures of the Rhodococcus proteasome with and without its pro-peptides: implications for the role of the pro-peptide in proteasome assembly.

Automatic solution of heavy-atom substructures.

Backbone dynamics of an oncogenic mutant of Cdc42Hs shows increased flexibility at the nucleotide-binding site.

Exploring the structural dynamics of the E.coli chaperonin GroEL using translation-libration-screw crystallographic refinement of intermediate states.

Crystal structure of a PhoU protein homologue: a new class of metalloprotein containing multinuclear iron clusters.

Crystal structure of DNA sequence specificity subunit of a type I restriction-modification enzyme and its functional implications.

Crystal structure of the "PhoU-like" phosphate uptake regulator from Aquifex aeolicus.

Crystal structure of a heat-inducible transcriptional repressor HrcA from Thermotoga maritima: structural insight into DNA binding and dimerization.

A robust bulk-solvent correction and anisotropic scaling procedure.

Crystal structure of a bacterial ribonuclease P RNA.

Automated crystallographic ligand building using the medial axis transform of an electron-density isosurface.

Structural genomics of minimal organisms and protein fold space.

Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP.

Structural basis for double-stranded RNA processing by Dicer.

Solution structure of an oncogenic mutant of Cdc42Hs.

Automated ligand fitting by core-fragment fitting and extension into density.

SPARX, a new environment for Cryo-EM image processing.

Ligand identification using electron-density map correlations.

Interpretation of ensembles created by multiple iterative rebuilding of macromolecular models.

On macromolecular refinement at subatomic resolution with interatomic scatterers.

Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard.

Surprises and pitfalls arising from (pseudo)symmetry.

Addressing the need for alternative transportation fuels: the Joint BioEnergy Institute.

A method for the prevention of thrombin-induced degradation of recombinant proteins.

Protein structures by spallation neutron crystallography.

Modeling membrane proteins utilizing information from silent amino acid substitutions.

Iterative-build OMIT maps: map improvement by iterative model building and refinement without model bias.

Automated structure solution with the PHENIX suite.

The protein structure initiative structural genomics knowledgebase.

Crystallographic model quality at a glance.

Phaser crystallographic software.

Generalized X-ray and neutron crystallographic analysis: more accurate and complete structures for biological macromolecules.

Decision-making in structure solution using Bayesian estimates of map quality: the PHENIX AutoSol wizard.

Structure of endoglucanase Cel9A from the thermoacidophilic Alicyclobacillus acidocaldarius.

NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42.

Automatic multiple-zone rigid-body refinement with a large convergence radius.

Averaged kick maps: less noise, more signal... and probably less bias.

Recent developments in phasing and structure refinement for macromolecular crystallography.

electronic Ligand Builder and Optimization Workbench (eLBOW): a tool for ligand coordinate and restraint generation.

A rapid and inexpensive labeling method for microarray gene expression analysis.

On the use of logarithmic scales for analysis of diffraction data.

Robust indexing for automatic data collection.

PHENIX: a comprehensive Python-based system for macromolecular structure solution.

Crystal structure of the transcriptional activator HlyU from Vibrio vulnificus CMCP6.

Raman imaging of cell wall polymers in Arabidopsis thaliana.

Crystal structures of a group II chaperonin reveal the open and closed states associated with the protein folding cycle.

Biochemical characterization and crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima.

Molecular simulations provide new insights into the role of the accessory immunoglobulin-like domain of Cel9A.

phenix.model_vs_data: a high-level tool for the calculation of crystallographic model and data statistics.

A microscale platform for integrated cell-free expression and activity screening of cellulases.

Evidence of functional protein dynamics from X-ray crystallographic ensembles.

High-throughput enzymatic hydrolysis of lignocellulosic biomass via in-situ regeneration.

Coupling of receptor conformation and ligand orientation determine graded activity.

Microfluidic glycosyl hydrolase screening for biomass-to-biofuel conversion.

Joint X-ray and neutron refinement with phenix.refine.

Targeted proteomics for metabolic pathway optimization: application to terpene production.

The Structural Biology Knowledgebase: a portal to protein structures, sequences, functions, and methods.

Exact direct-space asymmetric units for the 230 crystallographic space groups.

A switch I mutant of Cdc42 exhibits less conformational freedom.

The Phenix software for automated determination of macromolecular structures.

Blind image analysis for the compositional and structural characterization of plant cell walls.

A new generation of crystallographic validation tools for the protein data bank.

Raman-spectroscopy-based noninvasive microanalysis of native lignin structure.

Structure of a three-domain sesquiterpene synthase: a prospective target for advanced biofuels production.

Mechanism of nucleotide sensing in group II chaperonins.

iotbx.cif: a comprehensive CIF toolbox.

Supplementation of intracellular XylR leads to co-utilization of hemicellulose sugars.

Encoding substrates with mass tags to resolve stereospecific reactions using Nimzyme.