Ari Helenius

Membranes, viruses, detergents, and endosomes.

Virus entry: what has pH got to do with it?

Virus entry--an unwilling collaboration by the cell.

Host cell entry of respiratory syncytial virus involves macropinocytosis followed by proteolytic activation of the F protein.

Virus entry at a glance.

Architecture of respiratory syncytial virus revealed by electron cryotomography.

High-content analysis of sequential events during the early phase of influenza A virus infection.

Vaccinia virus entry is followed by core activation and proteasome-mediated release of the immunomodulatory effector VH1 from lateral bodies.

Role of DC-SIGN in Lassa virus entry into human dendritic cells.

Receptor concentration and diffusivity control multivalent binding of Sv40 to membrane bilayers.

siRNA screen of early poxvirus genes identifies the AAA+ ATPase D5 as the virus genome-uncoating factor.

Specific inhibition of diverse pathogens in human cells by synthetic microRNA-like oligonucleotides inferred from RNAi screens.

Genome-wide small interfering RNA screens reveal VAMP3 as a novel host factor required for Uukuniemi virus late penetration.

Large scale RNAi reveals the requirement of nuclear envelope breakdown for nuclear import of human papillomaviruses.

Endocytosis of viruses and bacteria.

Stepwise priming by acidic pH and a high K+ concentration is required for efficient uncoating of influenza A virus cores after penetration.

The host nonsense-mediated mRNA decay pathway restricts Mammalian RNA virus replication.

Influenza A virus uses the aggresome processing machinery for host cell entry.

Simultaneous analysis of large-scale RNAi screens for pathogen entry.

Vaccinia Virus Infection Requires Maturation of Macropinosomes.

HCMV Induces Macropinocytosis for Host Cell Entry in Fibroblasts.

A SPOPL/Cullin-3 ubiquitin ligase complex regulates endocytic trafficking by targeting EPS15 at endosomes.