Jonathan T. Butcher

Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments.

Porcine aortic valve interstitial cells in three-dimensional culture: comparison of phenotype with aortic smooth muscle cells.

Transcriptional profiles of valvular and vascular endothelial cells reveal phenotypic differences: influence of shear stress.

Valvular endothelial cells regulate the phenotype of interstitial cells in co-culture: effects of steady shear stress.

Equibiaxial strain stimulates fibroblastic phenotype shift in smooth muscle cells in an engineered tissue model of the aortic wall.

Quantitative volumetric analysis of cardiac morphogenesis assessed through micro-computed tomography.

Periostin promotes atrioventricular mesenchyme matrix invasion and remodeling mediated by integrin signaling through Rho/PI 3-kinase.

The next frontier in cardiovascular developmental biology--an integrated approach to adult disease?

Transitions in early embryonic atrioventricular valvular function correspond with changes in cushion biomechanics that are predictable by tissue composition.

Valvulogenesis: the moving target.

Valvular endothelial cells and the mechanoregulation of valvular pathology.

Mechanobiology of the aortic heart valve.

Neonatal and adult cardiovascular pathophysiological remodeling and repair: developmental role of periostin.

Cyclic strain regulates pro-inflammatory protein expression in porcine aortic valve endothelial cells.

Transforming growth factor β, bone morphogenetic protein, and vascular endothelial growth factor mediate phenotype maturation and tissue remodeling by embryonic valve progenitor cells: relevance for heart valve tissue engineering.

Two-photon microscopy-guided femtosecond-laser photoablation of avian cardiogenesis: noninvasive creation of localized heart defects.

Quantitative three-dimensional analysis of embryonic chick morphogenesis via microcomputed tomography.

Hemodynamic patterning of the avian atrioventricular valve.

Quantitative three-dimensional analysis of embryonic chick morphogenesis via microcomputed tomography.

Aortic valve disease and treatment: the need for naturally engineered solutions.

Quantitative three-dimensional imaging of live avian embryonic morphogenesis via micro-computed tomography.

Inflammatory regulation of valvular remodeling: the good(?), the bad, and the ugly.

Quantification of embryonic atrioventricular valve biomechanics during morphogenesis.

Cardiac developmental toxicity.

Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture.