Michael J. Yaszemski

Histocompatibility of photocrosslinked polyanhydrides: a novel in situ forming orthopaedic biomaterial.

Combined posterior pelvis and lumbar spine resection for sarcoma.

Bowel and bladder function after major sacral resection.

Relationship between surgical margins and local recurrence in sarcomas of the spine.

Controlled release of NFkappaB decoy oligonucleotides from biodegradable polymer microparticles.

Effects of NFkappaB decoy oligonucleotides released from biodegradable polymer microparticles on a glioblastoma cell line.

Biodegradable polymer grafts for surgical repair of the injured spinal cord.

Development of an injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations. Part 1. Encapsulation of marrow stromal osteoblasts in surface crosslinked gelatin microparticles.

Development of an injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations. Part 2. Viability of encapsulated marrow stromal osteoblasts cultured on crosslinking poly(propylene fumarate).

Development of an injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations. Part 3. Proliferation and differentiation of encapsulated marrow stromal osteoblasts cultured on crosslinking poly(propylene fumarate).

Metastatic disease of the spine: evaluation and treatment.

Attachment, proliferation, and migration of marrow stromal osteoblasts cultured on biomimetic hydrogels modified with an osteopontin-derived peptide.

Anatomic relationship of the internal carotid artery to the C1 vertebra: A case report of cervical reconstruction for chordoma and pilot study to assess the risk of screw fixation of the atlas.

Lumbar spine stabilization with a thoracolumbosacral orthosis: evaluation with video fluoroscopy.

Modulation of differentiation and mineralization of marrow stromal cells cultured on biomimetic hydrogels modified with Arg-Gly-Asp containing peptides.

Development of biodegradable poly(propylene fumarate)/poly(lactic-co-glycolic acid) blend microspheres. I. Preparation and characterization.

Development of biodegradable poly(propylene fumarate)/poly(lactic-co-glycolic acid) blend microspheres. II. Controlled drug release and microsphere degradation.

Quantitative analysis of interconnectivity of porous biodegradable scaffolds with micro-computed tomography.

Synthes Award for Resident Research in Spinal Cord & Spinal Column Injury: Surgical repair of the injured spinal cord using biodegradable polymer implants to facilitate axon regeneration.

Osteogenic differentiation of rat bone marrow stromal cells cultured on Arg-Gly-Asp modified hydrogels without dexamethasone and beta-glycerol phosphate.

Synthesis and characterizations of biodegradable and crosslinkable poly(epsilon-caprolactone fumarate), poly(ethylene glycol fumarate), and their amphiphilic copolymer.

Reconstruction after total sacrectomy: early experience with a new surgical technique.

Multiple-channel scaffolds to promote spinal cord axon regeneration.

Optimal segmentation of microcomputed tomographic images of porous tissue-engineering scaffolds.

Synthesis, material properties, and biocompatibility of a novel self-cross-linkable poly(caprolactone fumarate) as an injectable tissue engineering scaffold.

Chondroconductive potential of tantalum trabecular metal.

Operative management of sacral chordoma.

Development of a biologic prosthetic composite for cartilage repair.

Controlled drug release from a novel injectable biodegradable microsphere/scaffold composite based on poly(propylene fumarate).

Optimizing conditions and avoiding pitfalls for prolonged axonal tracing with carbocyanine dyes in fixed rat spinal cords.

Sacral osteomyelitis after ileal pouch-anal anastomosis: report of four cases.

Bone-tissue-engineering material poly(propylene fumarate): correlation between molecular weight, chain dimensions, and physical properties.

Local antibiotic delivery with OsteoSet, DBX, and Collagraft.

Mechanical effects of partial sacrectomy: when is reconstruction necessary?

Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death of osteosarcoma cells.

Poly(propylene fumarate) bone tissue engineering scaffold fabrication using stereolithography: effects of resin formulations and laser parameters.

Characterization of photo-cross-linked oligo[poly(ethylene glycol) fumarate] hydrogels for cartilage tissue engineering.

C1 anatomy and dimensions relative to lateral mass screw placement.

Engineering a noncarrier to a highly efficient carrier peptide for noncovalently delivering biologically active proteins into human cells.

Total en bloc spondylectomy of C5 vertebra for chordoma.

Potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): enhancing apoptosis.

Technology assessment: approach and reimbursement.

Fabrication and characterization of poly(propylene fumarate) scaffolds with controlled pore structures using 3-dimensional printing and injection molding.

Changes in red blood cell transfusion practice during the past two decades: a retrospective analysis, with the Mayo database, of adult patients undergoing major spine surgery.

Fixation strength of unicortical versus bicortical C1-C2 transarticular screws.

Symposium. The introduction of biologics in orthopaedics: issues of cost, commercialism, and ethics.

Methods for in vitro characterization of multichannel nerve tubes.

Two-dimensional digital video ankle motion analysis for assessment of function in the rat sciatic nerve model.

Biomechanical comparison of unicortical versus bicortical C1 lateral mass screw fixation.

Characterization of porous injectable poly-(propylene fumarate)-based bone graft substitute.

Biomechanical evaluation of an injectable radiopaque polypropylene fumarate cement for kyphoplasty in a cadaveric osteoporotic vertebral compression fracture model.

Synthesis and evaluation of novel biodegradable hydrogels based on poly(ethylene glycol) and sebacic acid as tissue engineering scaffolds.

Effect of hydrogel porosity on marrow stromal cell phenotypic expression.

Tissue engineering of bone: material and matrix considerations.

Photo-cross-linked hybrid polymer networks consisting of poly(propylene fumarate) and poly(caprolactone fumarate): controlled physical properties and regulated bone and nerve cell responses.

Targeted delivery of gemcitabine to pancreatic adenocarcinoma using cetuximab as a targeting agent.

Relationship of the internal carotid artery to the anterior aspect of the C1 vertebra: implications for C1-C2 transarticular and C1 lateral mass fixation.

2-methoxyestradiol-induced cell death in osteosarcoma cells is preceded by cell cycle arrest.

Physical properties and cellular responses to crosslinkable poly(propylene fumarate)/hydroxyapatite nanocomposites.

Retention of in vitro and in vivo BMP-2 bioactivities in sustained delivery vehicles for bone tissue engineering.

Non-invasive screening method for simultaneous evaluation of in vivo growth factor release profiles from multiple ectopic bone tissue engineering implants.

Development of biodegradable and injectable macromers based on poly(ethylene glycol) and diacid monomers.

Accuracy of motor axon regeneration across autograft, single-lumen, and multichannel poly(lactic-co-glycolic acid) nerve tubes.

Cellular uptake of gold nanoparticles directly cross-linked with carrier peptides by osteosarcoma cells.

Urgent surgical decompression compared to methylprednisolone for the treatment of acute spinal cord injury: a randomized prospective study in beagle dogs.

Effect of autologous bone marrow stromal cell seeding and bone morphogenetic protein-2 delivery on ectopic bone formation in a microsphere/poly(propylene fumarate) composite.

Rigid fixation of the spinal column improves scaffold alignment and prevents scoliosis in the transected rat spinal cord.

Nerve tubes for peripheral nerve repair.

Non-invasive monitoring of BMP-2 retention and bone formation in composites for bone tissue engineering using SPECT/CT and scintillation probes.

Photo-crosslinked poly(epsilon-caprolactone fumarate) networks for guided peripheral nerve regeneration: material properties and preliminary biological evaluations.

Neural stem cell- and Schwann cell-loaded biodegradable polymer scaffolds support axonal regeneration in the transected spinal cord.

Neurogenic tumors of the pelvis: clinicopathologic features and surgical outcomes using a multidisciplinary team.

Solute transport in cyclically deformed porous tissue scaffolds with controlled pore cross-sectional geometries.

Three-dimensional porous biodegradable polymeric scaffolds fabricated with biodegradable hydrogel porogens.

Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration.

Potential of hydrogels based on poly(ethylene glycol) and sebacic acid as orthopedic tissue engineering scaffolds.

The roles of matrix polymer crystallinity and hydroxyapatite nanoparticles in modulating material properties of photo-crosslinked composites and bone marrow stromal cell responses.

Relationship between scaffold channel diameter and number of regenerating axons in the transected rat spinal cord.

Axon regeneration through scaffold into distal spinal cord after transection.

Stimulation of neurite outgrowth using positively charged hydrogels.

Designing ideal conduits for peripheral nerve repair.

Metastatic bone disease: diagnosis, evaluation, and treatment.

Current tissue engineering and novel therapeutic approaches to axonal regeneration following spinal cord injury using polymer scaffolds.

Porous tantalum and poly-epsilon-caprolactone biocomposites for osteochondral defect repair: preliminary studies in rabbits.

Mesenchymal stem cells for bone repair and metabolic bone diseases.

The effects of postoperative ketorolac on wound healing in a rat model.

Importance of the vasculature in cyst formation after spinal cord injury.

Severe osteogenesis imperfecta in cyclophilin B-deficient mice.

2-methoxyestradiol-mediated anti-tumor effect increases osteoprotegerin expression in osteosarcoma cells.

Enhanced cell ingrowth and proliferation through three-dimensional nanocomposite scaffolds with controlled pore structures.

Augmentation of surgical angiogenesis in vascularized bone allotransplants with host-derived a/v bundle implantation, fibroblast growth factor-2, and vascular endothelial growth factor administration.

Collagen type I hydrogel allows migration, proliferation, and osteogenic differentiation of rat bone marrow stromal cells.

Germline TGF-beta receptor mutations and skeletal fragility: a report on two patients with Loeys-Dietz syndrome.

Metastatic bone disease: diagnosis, evaluation, and treatment.

Controlling dispersion of axonal regeneration using a multichannel collagen nerve conduit.

Video fluoroscopic analysis of the effects of three commonly-prescribed off-the-shelf orthoses on vertebral motion.

A biofilm approach to detect bacteria on removed spinal implants.

The development of electrically conductive polycaprolactone fumarate-polypyrrole composite materials for nerve regeneration.

Cross-linking characteristics and mechanical properties of an injectable biomaterial composed of polypropylene fumarate and polycaprolactone co-polymer.

In vivo biodegradation and biocompatibility of PEG/sebacic acid-based hydrogels using a cage implant system.

Enhanced bone morphogenetic protein-2-induced ectopic and orthotopic bone formation by intermittent parathyroid hormone (1-34) administration.

A stimuli-responsive hydrogel for doxorubicin delivery.

In vitro and in vivo release of nerve growth factor from biodegradable poly-lactic-co-glycolic-acid microspheres.

Photo-Crosslinked Poly(ε-caprolactone fumarate) Networks: Roles of Crystallinity and Crosslinking Density in Determining Mechanical Properties.

Development of electrically conductive oligo(polyethylene glycol) fumarate-polypyrrole hydrogels for nerve regeneration.

Introduction of new devices and technologies into a spine surgery practice: a review of processes and regulations.

Material properties and electrical stimulation regimens of polycaprolactone fumarate-polypyrrole scaffolds as potential conductive nerve conduits.

Growth factor interactions in bone regeneration.

Sustained delivery of dibutyryl cyclic adenosine monophosphate to the transected spinal cord via oligo [(polyethylene glycol) fumarate] hydrogels.

The effects of fixed electrical charge on chondrocyte behavior.

COL1 C-propeptide cleavage site mutations cause high bone mass osteogenesis imperfecta.

Rat sciatic nerve repair with a poly-lactic-co-glycolic acid scaffold and nerve growth factor releasing microspheres.

Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow.

Osteoblast growth and bone-healing response to three-dimensional poly(ε-caprolactone fumarate) scaffolds.

High-resolution genomic mapping reveals consistent amplification of the fibroblast growth factor receptor substrate 2 gene in well-differentiated and dedifferentiated liposarcoma.

Comparison of polymer scaffolds in rat spinal cord: a step toward quantitative assessment of combinatorial approaches to spinal cord repair.

Reformulating polycaprolactone fumarate to eliminate toxic diethylene glycol: effects of polymeric branching and autoclave sterilization on material properties.

Prospective assessment of patient morbidity from prone sacral positioning.

Controlled release of vascular endothelial growth factor using poly-lactic-co-glycolic acid microspheres: in vitro characterization and application in polycaprolactone fumarate nerve conduits.

Effects of composite formulation on the mechanical properties of biodegradable poly(propylene fumarate)/bone fiber scaffolds.

Aneurysmal bone cyst of the cervical spine in children.

Incorporation of phosphate group modulates bone cell attachment and differentiation on oligo(polyethylene glycol) fumarate hydrogel.

Regulation of interferon pathway in 2-methoxyestradiol-treated osteosarcoma cells.

Short- and long-term peripheral nerve regeneration using a poly-lactic-co-glycolic-acid scaffold containing nerve growth factor and glial cell line-derived neurotrophic factor releasing microspheres.

Fusion of dynactin 1 to anaplastic lymphoma kinase in inflammatory myofibroblastic tumor.

Cryoablation of recurrent sacrococcygeal tumors.

A systematic review of animal models used to study nerve regeneration in tissue-engineered scaffolds.

Controlled release of doxorubicin from pH-responsive microgels.

Histone deacetylase 3 is required for maintenance of bone mass during aging.

Delayed repair of the peripheral nerve: a novel model in the rat sciatic nerve.

Hydrogel-PLGA delivery system prolongs 2-methoxyestradiol-mediated anti-tumor effects in osteosarcoma cells.

RNA-dependent protein kinase is essential for 2-methoxyestradiol-induced autophagy in osteosarcoma cells.

MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.

Comparison and characterization of multiple biomaterial conduits for peripheral nerve repair.

Biomechanical evaluation of an injectable and biodegradable copolymer P(PF-co-CL) in a cadaveric vertebral body defect model.

Gait cycle analysis: parameters sensitive for functional evaluation of peripheral nerve recovery in rat hind limbs.

Implantation of cauda equina nerve roots through a biodegradable scaffold at the conus medullaris in rat.

Non-invasive isometric force measurement of plantar flexors in rats.

A new type of reconstruction of the hemipelvis after type 3 amputative sacrectomy using pedicled fibula: technical note.

Comparison of cellular architecture, axonal growth, and blood vessel formation through cell-loaded polymer scaffolds in the transected rat spinal cord.

Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma.

ASTM international workshop on standards and measurements for tissue engineering scaffolds.

Key changes in denervated muscles and their impact on regeneration and reinnervation.

Nanocomposite bone scaffolds based on biodegradable polymers and hydroxyapatite.

Effect of calcium phosphate coating and rhBMP-2 on bone regeneration in rabbit calvaria using poly(propylene fumarate) scaffolds.

Tissue engineered constructs: perspectives on clinical translation.

Repair of osteochondral defects in the minipig model by OPF hydrogel loaded with adipose-derived mesenchymal stem cells.

Positively Charged Oligo[Poly(Ethylene Glycol) Fumarate] Scaffold Implantation Results in a Permissive Lesion Environment after Spinal Cord Injury in Rat.

Does CT-based Rigidity Analysis Influence Clinical Decision-making in Simulations of Metastatic Bone Disease?

Positively Charged Oligo[Poly(Ethylene Glycol) Fumarate] Scaffold Implantation Results in a Permissive Lesion Environment after Spinal Cord Injury in Rat.

Inhibition of Autophagy Increases 2-Methoxyestradiol-Induced Cytotoxicity in SW1353 Chondrosarcoma Cells.

Ligament Tissue Engineering Using a Novel Porous Polycaprolactone Fumarate Scaffold and Adipose Tissue-Derived Mesenchymal Stem Cells Grown in Platelet Lysate.

Expansile crosslinked polymersomes for pH sensitive delivery of doxorubicin.

Controlled Delivery of Vancomycin via Charged Hydrogels.

Surgical Therapies and Tissue Engineering: At the Intersection Between Innovation and Regulation.

Tunable tissue scaffolds fabricated by in situ crosslink in phase separation system.

Novel biodegradable poly(propylene fumarate)-co-poly(l-lactic acid) porous scaffolds fabricated by phase separation for tissue engineering applications.

How Does the Level of Nerve Root Resection in En Bloc Sacrectomy Influence Patient-Reported Outcomes?

Perioperative complications in open versus percutaneous treatment of spinal fractures in patients with an ankylosed spine.

Hydrolysable core crosslinked particle for receptor-mediated pH-sensitive anticancer drug delivery.

Noninvasive Failure Load Prediction of Vertebrae with Simulated Lytic Defects and Biomaterial Augmentation.

Hypoxia-related microRNA-210 is a diagnostic marker for discriminating osteoblastoma and osteosarcoma.

Quantitative Computed Tomography Protocols Affect Material Mapping and Quantitative Computed Tomography-Based Finite-Element Analysis Predicted Stiffness.

The Value of Systematic Reviews in Estimating the Cost and Barriers to Translation in Tissue Engineering.

Novel porous poly(propylene fumarate-co-caprolactone) scaffolds fabricated by thermally induced phase separation.

Safety of Intra-Articular Implantation of Oligo[Poly(ethylene glycol) Fumarate] Scaffolds into the Rabbit Knee.

Molecular strategies for modulating Wnt signaling.

A New Vertebral Body Replacement Strategy Using Expandable Polymeric Cages.

2-Methoxyestradiol-Mediated Induction of Frzb Contributes to Cell Death and Autophagy in MG63 Osteosarcoma Cells.

Invertible micellar polymer nanoassemblies target bone tumor cells but not normal osteoblast cells.

Effect of different sustained bone morphogenetic protein-2 release kinetics on bone formation in poly(propylene fumarate) scaffolds.

GDNF Schwann cells in hydrogel scaffolds promote regional axon regeneration, remyelination and functional improvement after spinal cord transection in rats.

Inhibiting DNA-PKCS radiosensitizes human osteosarcoma cells.

Chondrocyte Attachment, Proliferation, and Differentiation on Three-Dimensional Polycaprolactone Fumarate Scaffolds.

Total lumbar facetectomy without fusion: short and long term follow-up in a single surgeon series.

A Combination of a Polycaprolactone Fumarate Scaffold with Polyethylene Terephthalate Sutures for Intra-Articular Ligament Regeneration.

FH535 Suppresses Osteosarcoma Growth In Vitro and Inhibits Wnt Signaling through Tankyrases.

Leadership, Communication, and Negotiation Across a Diverse Workforce*: An AOA Critical Issues Symposium.

Outcomes and Complications of Reconstruction with Use of Free Vascularized Fibular Graft for Spinal and Pelvic Defects Following Resection of a Malignant Tumor.

Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?