Sieghart Sopper

Cytokine levels in CSF and neuropsychological performance in HIV patients.

The Role of the Envelope Glycoprotein in the Depletion of T Helper Cells in Human Immunodeficiency Virus Infection.

Caspase inhibition activates HIV in latently infected cells. Role of tumor necrosis factor receptor 1 and CD95.

Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes.

Impact of simian immunodeficiency virus (SIV) infection on lymphocyte numbers and T-cell turnover in different organs of rhesus monkeys.

Replication, immunogenicity, and protective properties of live-attenuated simian immunodeficiency viruses expressing interleukin-4 or interferon-gamma.

Caspase inhibitors as a supplement in immune activation therapies to achieve eradication of HIV in its latent reservoirs.

HIV-infection of the central nervous system: the tightrope walk of innate immunity.

Early impairment in dopaminergic neurotransmission in brains of SIV-infected rhesus monkeys due to microglia activation.

Caspase inhibition in apoptotic T cells triggers necrotic cell death depending on the cell type and the proapoptotic stimulus.

Enrichment and persistence of virus-specific CTL in the brain of simian immunodeficiency virus-infected monkeys is associated with a unique cytokine environment.

Intrathecal viral replication and cerebral deficits in different stages of human immunodeficiency virus disease.

Memantine upregulates BDNF and prevents dopamine deficits in SIV-infected macaques: a novel pharmacological action of memantine.

Disruption of excitatory amino acid transporters in brains of SIV-infected rhesus macaques is associated with microglia activation.

CD4 deficits and disease course acceleration can be driven by a collapse of the CD8 response in rhesus macaques infected with simian immunodeficiency virus.

Mucosal prior to systemic application of recombinant adenovirus boosting is more immunogenic than systemic application twice but confers similar protection against SIV-challenge in DNA vaccine-primed macaques.

Susceptibility to Simian immunodeficiency virus ex vivo predicts outcome of a prime-boost vaccine after SIVmac239 challenge.

Measurement of soluble inflammatory mediators in cerebrospinal fluid of human immunodeficiency virus-positive patients at distinct stages of infection by solid-phase protein array.

Flow cytometric characterization of the lymphocyte composition in a variety of mucosal tissues in healthy rhesus macaques.

Definition of leukocyte subsets in primate central nervous system by polychromatic flow cytometry.

Potential role of regulatory T cells in reversing obesity-linked insulin resistance and diabetic nephropathy.

Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys.

DyeCycle Violet used for side population detection is a substrate of P-glycoprotein.

Stable multi-infection of splenocytes during SIV infection--the basis for continuous recombination.

Increases in CSF dopamine in HIV patients are due to the dopamine transporter 10/10-repeat allele which is more frequent in HIV-infected individuals.

Host factors determine differential disease progression after infection with nef-deleted simian immunodeficiency virus.

Identification of molecular sub-networks associated with cell survival in a chronically SIVmac-infected human CD4+ T cell line.

The side population of ovarian cancer cells defines a heterogeneous compartment exhibiting stem cell characteristics.

Characterization of B and plasma cells in blood, bone marrow, and secondary lymphoid organs of rhesus macaques by multicolor flow cytometry.

Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.

Treg(s) in Cancer: Friends or Foe?

OMIP-026: Phenotypic analysis of B and plasma cells in rhesus macaques.

Drug Transporter-Mediated Protection of Cancer Stem Cells From Ionophore Antibiotics.

Noncytolytic CD8+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Macaques.

Increased BST2 expression during simian immunodeficiency virus infection is not a determinant of disease progression in rhesus monkeys.

Optimized Stem Cell Detection Using the DyeCycle-Triggered Side Population Phenotype.

Opiate receptor blockade on human granulosa cells inhibits VEGF release.

Leukemic Stem Cell Quantification in Newly Diagnosed Patients With Chronic Myeloid Leukemia Predicts Response to Nilotinib Therapy.

High prevalence of side population in human cancer cell lines.

Successful management of mixed chimerism after bone marrow transplant in beta-thalassemia major.

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.

Ionophore Antibiotics as Cancer Stem Cell-Selective Drugs: Open Questions.

Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche.

Pre-infection transcript levels of FAM26F in peripheral blood mononuclear cells inform about overall plasma viral load in acute and post-acute phase after simian immunodeficiency virus infection.

Reduced CD62L Expression on T Cells and Increased Soluble CD62L Levels Predict Molecular Response to Tyrosine Kinase Inhibitor Therapy in Early Chronic-Phase Chronic Myelogenous Leukemia.

Single cell immune profiling by mass cytometry of newly diagnosed chronic phase chronic myeloid leukemia treated with nilotinib.

The influence of stromal cells and tumor-microenvironment-derived cytokines and chemokines on CD3(+)CD8(+) tumor infiltrating lymphocyte subpopulations.