Muriel Cuendet

Constituents of the bark and twigs of Artocarpus dadah with cyclooxygenase inhibitory activity.

Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrol.

Bioactive constituents of the seeds of Brucea javanica.

Prenylated flavonoids of the leaves of Macaranga conifera with inhibitory activity against cyclooxygenase-2.

Activity-guided fractionation of the seeds of Ziziphus jujuba using a cyclooxygenase-2 inhibitory assay.

Chemical and biological investigation of the fungus Pulveroboletus ravenelii.

Potential cancer chemopreventive constituents of the leaves of Macaranga triloba.

Multiple myeloma regression mediated by bruceantin.

Antitumor activity of bruceantin: an old drug with new promise.

Brusatol-induced HL-60 cell differentiation involves NF-kappaB activation.

Constituents of Asparagus officinalis evaluated for inhibitory activity against cyclooxygenase-2.

Equine estrogen metabolite 4-hydroxyequilenin induces anchorage-independent growth of human mammary epithelial MCF-10A cells: differential gene expression.

Natural inhibitors of carcinogenesis.

Constituents of the seeds of Hernandia ovigera with inhibitory activity against cyclooxygenase-2.

Biologic evaluation of curcumin and structural derivatives in cancer chemoprevention model systems.

Constituents of the stems of Macrococculus pomiferus and their inhibitory activities against cyclooxygenases-1 and -2.

Altered apoptotic response in MCF 10A cells treated with the equine estrogen metabolite, 4-hydroxyequilenin.

Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense).

Quinone reductase induction as a biomarker for cancer chemoprevention.

Potential cancer chemopreventive agents from Arbutus unedo.

Response of human mammary epithelial cells to DNA damage induced by 4-hydroxyequilenin: Lack of p53-mediated G1 arrest.

A comparative evaluation of the anticancer properties of European and American elderberry fruits.

Synthesis and cancer chemopreventive activity of zapotin, a natural product from Casimiroa edulis.

An ELISA method to measure inhibition of the COX enzymes.

Synthesis and biological evaluation of (+/-)-abyssinone II and its analogues as aromatase inhibitors for chemoprevention of breast cancer.

Synthesis and biological evaluation of a library of resveratrol analogues as inhibitors of COX-1, COX-2 and NF-kappaB.

Zapotin prevents mouse skin tumorigenesis during the stages of initiation and promotion.

Cancer chemopreventive activity and metabolism of isoliquiritigenin, a compound found in licorice.

Pleiotropic mechanisms facilitated by resveratrol and its metabolites.

Advanced methods for natural product drug discovery in the field of nutraceuticals.

Acylated pregnane glycosides from Caralluma sinaica.

In 2005, the School of Pharmaceutical Sciences of the University of Geneva and Lausanne was inaugurated. Introduction.

Plants as a source of therapeutic and health products.

HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

Cancer chemopreventive diterpenes from Salvia corrugata.

Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway.

Chemical composition of the bark of Tetrapterys mucronata and identification of acetylcholinesterase inhibitory constituents.

Isolation and biological activity of compounds from Garcinia preussii.

Rapid identification of coumarins from Micromelum falcatum by UPLC-HRMS/MS and targeted isolation of three new derivatives.

Antitrypanosomal quinoline alkaloids from the roots of Waltheria indica.

Aurones as histone deacetylase inhibitors: identification of key features.

Reverse pharmacology for developing an anti-malarial phytomedicine. The example of Argemone mexicana.

Cytotoxic flavonoids and other constituents from the stem bark of Ochna schweinfurthiana.

Chemical constituents from Waltheria indica exert in vitro activity against Trypanosoma brucei and T. cruzi.

Prevention of False-Positive Results: Development of an HPTLC Autographic Assay for the Detection of Natural Tyrosinase Inhibitors.

Investigation on the ZBG-functionality of phenyl-4-yl-acrylohydroxamic acid derivatives as histone deacetylase inhibitors.

Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates.

Antifungal Quinoline Alkaloids from Waltheria indica.

Biphenyl-4-yl-acrylohydroxamic acids: Identification of a novel indolyl-substituted HDAC inhibitor with antitumor activity.

Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures.

Cell-based multi-substrate assay coupled to UHPLC-ESI-MS/MS for a quick identification of class-specific HDAC inhibitors.

Bruceantin inhibits multiple myeloma cancer stem cell proliferation.

Synthesis of a selective HDAC6 inhibitor active in neuroblasts.

UHPLC-MS-based HDAC Assay Applied to Bio-guided Microfractionation of Fungal Extracts.

Cutaneous iontophoresis of μ-conotoxin CnIIIC-A potent NaV1.4 antagonist with analgesic, anaesthetic and myorelaxant properties.

Novel histone deacetylase 6 (HDAC6) selective inhibitors: a patent evaluation (WO2014181137).

Synthesis of an Uncharged Tetra-cyclopeptide Acting as a Transmembrane Carrier: Enhanced Cellular and Nuclear Uptake.

Epigenetic strategies to reverse drug resistance in heterogeneous multiple myeloma.

Cancer chemopreventive activity of compounds isolated from Waltheria indica.

Targeting Multiple Myeloma Cancer Stem Cells with Natural Products - Lessons from Other Hematological Malignancies.