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Molecular,
Cellular,
and Developmental Biology Program,
Department of Biological Chemistry and Pharmacology,
Molecular, Cellular, and Developmental Biology Program
Chen Gu has not added Biography.
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The microtubule plus-end tracking protein EB1 is required for Kv1 voltage-gated K+ channel axonal targeting.
Neuron Dec, 2006 | Pubmed ID: 17145502
The axon-dendrite targeting of Kv3 (Shaw) channels is determined by a targeting motif that associates with the T1 domain and ankyrin G.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2007 | Pubmed ID: 18094255
Dynamics of Kv1 channel transport in axons.
PloS one Aug, 2010 | Pubmed ID: 20694152
Polarized targeting of L1-CAM regulates axonal and dendritic bundling in vitro.
The European journal of neuroscience Nov, 2010 | Pubmed ID: 20964729
Kinesin I transports tetramerized Kv3 channels through the axon initial segment via direct binding.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2010 | Pubmed ID: 21106837
Function and mechanism of axonal targeting of voltage-sensitive potassium channels.
Progress in neurobiology Jul, 2011 | Pubmed ID: 21530607
Clustering and activity tuning of Kv1 channels in myelinated hippocampal axons.
The Journal of biological chemistry Jul, 2011 | Pubmed ID: 21602278
Alternative splicing regulates kv3.1 polarized targeting to adjust maximal spiking frequency.
The Journal of biological chemistry Jan, 2012 | Pubmed ID: 22105078
K+ channel alterations in the progression of experimental autoimmune encephalomyelitis.
Neurobiology of disease Aug, 2012 | Pubmed ID: 22560931
Coupling mechanical forces to electrical signaling: molecular motors and the intracellular transport of ion channels.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry Apr, 2013 | Pubmed ID: 22910031
Myelination of rodent hippocampal neurons in culture.
Nature protocols Oct, 2012 | Pubmed ID: 22955693
Heteromerization of ciliary G protein-coupled receptors in the mouse brain.
PloS one , 2012 | Pubmed ID: 23029470
Kv3 channel assembly, trafficking and activity are regulated by zinc through different binding sites.
The Journal of physiology May, 2013 | Pubmed ID: 23420657
Activation of conventional kinesin motors in clusters by Shaw voltage-gated K+ channels.
Journal of cell science May, 2013 | Pubmed ID: 23487040
Astrocytes differentially respond to inflammatory autoimmune insults and imbalances of neural activity.
Acta neuropathologica communications Oct, 2013 | Pubmed ID: 24252623
Ankyrin-G directly binds to kinesin-1 to transport voltage-gated Na+ channels into axons.
Developmental cell Jan, 2014 | Pubmed ID: 24412576
Physiological and pathological functions of mechanosensitive ion channels.
Molecular neurobiology Oct, 2014 | Pubmed ID: 24532247
Regulation of neurovascular coupling in autoimmunity to water and ion channels.
Autoimmunity reviews Mar, 2015 | Pubmed ID: 25462580
TRPM2 ion channels regulate macrophage polarization and gastric inflammation during Helicobacter pylori infection.
Mucosal immunology 03, 2017 | Pubmed ID: 27435104
KIR4.1: K Channel Illusion or Reality in the Autoimmune Pathogenesis of Multiple Sclerosis.
Frontiers in molecular neuroscience , 2016 | Pubmed ID: 27729847
Polarity of varicosity initiation in central neuron mechanosensation.
The Journal of cell biology 07, 2017 | Pubmed ID: 28606925
Pre-culture Sudan Black B treatment suppresses autofluorescence signals emitted from polymer tissue scaffolds.
Scientific reports Aug, 2017 | Pubmed ID: 28827657
Suppression of Inflammatory Demyelinaton and Axon Degeneration through Inhibiting Kv3 Channels.
Frontiers in molecular neuroscience , 2017 | Pubmed ID: 29123469
Regulation of Central Nervous System Myelination in Higher Brain Functions.
Neural plasticity , 2018 | Pubmed ID: 29692804
The Ohio State University
Dustin Servello1,
Yuanzheng Gu2,3,
Chen Gu1,2
1Molecular, Cellular, and Developmental Biology Program, The Ohio State University,
2Department of Biological Chemistry and Pharmacology, The Ohio State University,
3, Biogen
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